Endocrine Disruptors: The Next Generation of Regulatory Concern?

McGovern, Patricia; McDonald, Howard

doi:10.2175/193864701790860588

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…For example, the metamorphosis of fertilized frog eggs was inhibited by low levels of perchlorate after a 70-day exposure, but not after the 14-day exposure recommended by the Endocrine Disrupter Screening and Testing Advisory Committee's (EDSTAC) method for testing EDCs (McDonald and McDonald, 2003). Furthermore, in a realistic scenario, aquatic organisms would be exposed to EDCs during entire life cycles.…”

Section: Health Effects (Human and Ecological)mentioning

confidence: 99%

“…Reports have shown that as much as 50% to 90% of an administered drug can be excreted in original form or a similar biologically active form (Braghetta et al, 2002;McGovern and McDonald, 2003). In sewage treatment plant discharges, PPCPs and endocrine disrupting compounds (EDCs) may be present as a result of incomplete removal during treatment, from combined sewage and storm water overflows, illicit connections, or leaking septic systems.…”

Section: Introductionmentioning

confidence: 99%

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Presence of Pharmaceuticals and Pesticides in Detroit River Water and the Effect of Ozone on Removal

Jasim¹,

Irabelli

Yang³

et al. 2006

Ozone: Science & Engineering

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Reports by different scientific groups indicate concern about traces of drugs that could make their way into tap water. Studies indicate that activated carbon and ozone are promising treatment methods to remove traces of pharmaceuticals and pesticides. The Windsor Utilities Commission (WUC), Windsor, Ontario, Canada, evaluated the occurrence of pharmaceuticals and endocrine disrupting chemicals in its raw water supply, and the effectiveness of ozone in removing these compounds. The analysis indicated that trace levels of compounds such as carbamazepine, caffeine, cotinine, and atrazine were detected in raw water and that treatment with ozone resulted in a greater removal versus conventional treatment.

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Section: Health Effects (Human and Ecological)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Presence of Pharmaceuticals and Pesticides in Detroit River Water and the Effect of Ozone on Removal

Jasim¹,

Irabelli

Yang³

et al. 2006

Ozone: Science & Engineering

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show abstract

“…issue McGovern and McDonald (2001). reviewed the current state of knowledge on more than 500 EDCs that are widely used and that have been widely detected in the environment.…”

mentioning

confidence: 99%

Emerging Chemicals and Analytical Methods

Morley¹,

Snow²,

Fox³

et al. 2003

Water Environment Research

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Emerging Pollutants as Endocrine Disruptors

Filho¹,

Santos²,

Vieira³

2007

Ecotoxicol. Environ. Contam.

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Emerging pollutants, such as pharmaceutical products, natural and synthetic hormones, pesticides, tensoactive substances, low-molecular-mass polymers, veterinary products, solvents and other organic contaminants present in urban and industrial effluents may act as endocrine disruptors (ED). The presence of such chemical species in the biota can lead to reproductive dysfunction and studies have shown they may also cause cancer. For humans, despite the fact that conclusive cause-and-effect relations have not yet been established, several published papers have indicated that a wide range of disorders, such as inborn impairments, behavioral and neurological alterations, immune deficiency, accelerated puberty, quality of semen and cancers (thyroid, breast, ovary, prostate, testicles) can be credited to endocrine disruptors emerging pollutants. The problem is more accentuated in developing countries, where environmental legislation is often poor, out of date and, as result does not consider substances with endocrine disrupting potential. In addition, the lack of basic sanitation aggravates the situation. In Brazil, for instance, approximately 80% of urban centers do not have any form of sewage treatment. Consequently, emerging pollutants enter the ecosystem through several paths generating threat to biota and, because of this, it represent an area which requires urgent attention, discussion and management.

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Endocrine Disruptors: The Next Generation of Regulatory Concern?

Cited by 3 publications

References 9 publications

Presence of Pharmaceuticals and Pesticides in Detroit River Water and the Effect of Ozone on Removal

Presence of Pharmaceuticals and Pesticides in Detroit River Water and the Effect of Ozone on Removal

Emerging Chemicals and Analytical Methods

Emerging Pollutants as Endocrine Disruptors

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