Endocrine-disruption potential of perfluoroethylcyclohexane sulfonate (PFECHS) in chronically exposed Daphnia magna

Transcriptomic, cellular and life-history responses of Daphnia magna chronically exposed to benzotriazoles: Endocrine-disrupting potential and molting effects

“…Ecdysteroids have been shown to induce vitellogenesis and increase vtg mRNA levels in most crustacean species [ 91 , 92 ] and in D . magna , the down-regulation of vtg transcription was observed in response to chronic exposure to JHAs [ 90 ] and to perfluoroethylcyclohexane sulfonate [ 93 ]. In the latter study, the VTG protein content was also decreased in exposed organisms, along with the up-regulation of cuticle coding genes [ 93 ].…”

“…magna , the down-regulation of vtg transcription was observed in response to chronic exposure to JHAs [ 90 ] and to perfluoroethylcyclohexane sulfonate [ 93 ]. In the latter study, the VTG protein content was also decreased in exposed organisms, along with the up-regulation of cuticle coding genes [ 93 ]. The observed vtg gene induction in the present study suggests therefore that BTR interferes with endocrine-mediated processes in D .…”

Monitoring of emerging contaminants of concern in the aquatic environment: a review of studies showing the application of effect-based measures

“…VTG secretion, unique to female sh species, has been widely used in different studies as a marker of feminisation in different male sh species due to estrogenic inuence of contaminants in water bodies. 78,85,[125][126][127][128][129][130][131][132][133] Assessment of VTG expression is oen used in conjunction with other estrogenicity bioassays as a complementary method for assessment of endocrine disruption within aquatic fauna. Such application was employed by Geraudie et al (2017) and Ganser et al (2019) in their studies where YES assay was used to evaluate estogenicity of water samples in addition to the VTG assay.…”

PFASs in the Nordic environment

“…For example, De Silva et al has reported the concentration of PFECHS in surface water (0.16-5.65 ng/L) and top predator fish (<MDL-3.7 ng/g ww in whole body homogenate) from the Great Lakes in Canada . Houde et al measured PFECHS in the surface water (1.04-1.38 ng/L) and fish (liver, 0.54±0.25 ng/g ww and plasma, 5.07±4.72 ng/g downstream the WWTP in the St. Lawrence river in Canada (Houde et al, 2013, Houde et al, 2016. The median surface water (0.13 ng/L) and fish liver (69.6 ng/g ww) concentrations of PFECHS was also been reported at a pond downstream of the Beijing Capital International Airport in China (Wang et al, 2016).…”