Endocrine Aspects of Cancer

Nathanson, Ira T.

doi:10.1056/nejm194412072312304

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Bole Of Estrogens1

Factors Bearing On the Incidence Of Breast Cancer1

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1949

1963

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Cited by 24 publications

(3 citation statements)

References 9 publications

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“…He thought this predisposition might be of a genetic character. Others (3, 32) have pointed out that a liberating influence on such a predisposed tissue would require an exposure level to estrogen above that normally used therapeutically; apparently a special individual susceptibility would be a prerequisite (58).…”

Section: Bole Of Estrogensmentioning

confidence: 99%

“…Over‐all, it does not appear to have increased since the advent of the widespread use of estrogens. Some authors (3, 6, 18, 26, 58) assert that susceptibility to breast cancer is related to a familial tendency. The relation of a familial pattern to the development of neoplasms in the male breast has not been fully elucidated.…”

Section: Factors Bearing On the Incidence Of Breast Cancermentioning

confidence: 99%

“…The effect of estrogen therapy as a carcinogenic agent is also a question of great importance. It seemed pertinent, therefore, to review the literature on the subject (1–75), and to add the following case report…”

mentioning

confidence: 99%

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