Endocan levels in children with renal hypodysplasia

Çaycı, Fatma Şemsa; Aydin, Zehra; Aygar, İsmail Selçuk; Avcı, Begüm; İnözü, Mihriban; Aksoy, Özlem Yüksel; Bayrakçı, Umut Selda

doi:10.5414/cn110402

Cited by 1 publication

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“…In renal hypodysplasia, which is one of the causes of chronic kidney disease, serum endocan levels were found to be significantly higher than in the control group. 46 It is known that rheumatic heart disease causes typical chronic fibrotic changes in the heart valves. This study, which was conducted to answer the question of whether endocan, a marker of fibrosis, can distinguish these patients from patients with nonrheumatic aortic regurgitation, is the first study on the subject and points to promising results in this regard.…”

Section: Discussionmentioning

confidence: 99%

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Serum endocan levels in children with rheumatic aortic insufficiency: can it differentiate bicuspid aortic valve disease from rheumatic heart disease?

Laloğlu

Ceviz

et al. 2022

Cardiol Young

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Aim: In this study, it was aimed to examine the serum endocan levels in patients with rheumatic aortic regurgitation and to investigate whether it has a value in differentiating it from aortic regurgitation due to bicuspid aortic valve. Methods: Blood samples were collected from patients with rheumatic aortic regurgitation (Group 1), incidentally diagnosed patients with borderline or definite rheumatic aortic regurgitation (Group 2), children with bicuspid aortic valve accompanied by aortic regurgitation (Group 3) and healthy children (Group 4) of similar age. Results: There were 12 children in Group 1, 13 in Group 2, 25 in Group 3, and 25 in Group 4. Groups were similar in terms of age (p = 0.291). There was no statistically significant difference between median serum endocan levels of Group 1 and Group 2 (p = 0.624), and Group 3 and Group 4 (p = 0.443). Despite that, the median serum endocan levels of Group 1 and Group 2 were significantly higher than that of both Group 3 and Group 4 (p = 0.000 for all). Conclusions: Our results indicate that serum endocan level can be used to differentiate rheumatic aortic regurgitation from non-rheumatic aortic regurgitation. It is thought that the prognostic role of this marker should be confirmed in long-term, prospective studies with larger samples.

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Section: Discussionmentioning

confidence: 99%

“…In renal hypodysplasia, which is one of the causes of chronic kidney disease, serum endocan levels were found to be significantly higher than in the control group. 46…”

Section: Discussionmentioning

confidence: 99%

Serum endocan levels in children with rheumatic aortic insufficiency: can it differentiate bicuspid aortic valve disease from rheumatic heart disease?

Laloğlu

Ceviz

et al. 2022

Cardiol Young

View full text Add to dashboard Cite

show abstract

Endocan levels in children with renal hypodysplasia

Cited by 1 publication

References 0 publications

Serum endocan levels in children with rheumatic aortic insufficiency: can it differentiate bicuspid aortic valve disease from rheumatic heart disease?

Serum endocan levels in children with rheumatic aortic insufficiency: can it differentiate bicuspid aortic valve disease from rheumatic heart disease?

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