Endobronchial Lipoma

Liew, CJ; Tham, KY; Poh, AC; Tee, A

doi:10.11622/smedj.2017015

Cited by 5 publications

(5 citation statements)

References 5 publications

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“…EL is characterized by expansive growth, potentially causing partial or complete obstruction of pulmonary segments, lobes, or even the main bronchi. In this study, six cases were located in the right lung and three cases in the left lung, consistent with previous literature studies, indicating a higher prevalence in the right lung [ 2 , 12 ]. EL is typically solitary and unilateral, although multiple cases have been reported [ 7 ].…”

Section: Discussionsupporting

confidence: 92%

Endobronchial Lipoma: A Rare Cause of Bronchial Stenosis or Obstruction

Chen,

Xin,

Pan

et al. 2023

Canadian Respiratory Journal

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Endobronchial lipoma (EL) is a rare benign tumor characterized by tracheobronchial smooth-surfaced mass, often resulting in bronchial obstruction without standard guidelines for management. This study seeks to clarify the clinical features and interventions of EL, aiming to improve its diagnosis and outcomes. A retrospective review was conducted on 28516 outpatients treated between January 2015 and December 2019 at the Department of Respiratory and Critical Care Medicine of the Second Affiliated Hospital of Air Force Medical University to collect patients diagnosed with EL. Their clinical, bronchoscopic, chest imaging, and histopathological features along with management were analyzed. Among the patients reviewed, nine were histopathologically diagnosed with EL, comprising seven males and two females. All EL patients exhibited noticeable symptoms, including cough (in eight patients), dyspnea (in six patients), fever (in three patients), expectoration (in two patients), chest pain (in two patients), hemoptysis (in one patient), and fatigue (in one patient). Chest CT abnormalities included endobronchial mass (in four patients), inflammatory exudation (in three patients), atelectasis (in three patients), and infiltration or consolidation (in two patients). In three patients, imaging showed fat density, directly leading to the diagnosis of EL. The EL lesions were distributed with six in the right lung and three in the left lung, all located within the first three subdivisions of the tracheobronchial tree. Treatment approaches varied, with one patient undergoing combined bronchoscopic resection and surgery. The remaining patients received bronchoscopic intervention such as electrosurgical snare resection, argon plasma coagulation (APC), cryotherapy, and holmium laser. Histopathological analysis confirmed the EL diagnosis. Finally, the mass removal restored bronchus patency. Taken together, EL symptoms lack specificity, necessitating reliance on histopathology for EL accurate diagnosis. Bronchoscopic interventions emerge as the preferred option for EL management, surpassing surgical approaches.

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Section: Discussionsupporting

confidence: 92%

Endobronchial Lipoma: A Rare Cause of Bronchial Stenosis or Obstruction

Chen,

Xin,

Pan

et al. 2023

Canadian Respiratory Journal

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“…Most of them are found in middleaged adults with a 90% male predominance [3,4]. Symptoms are nonspecific and result from a fixed bronchial obstruction, typically presenting with a cough or asthma-like symptoms that are not responsive to bronchodilators, and with normal PFTs [5]. Our patient's main symptom was cough with some occasional dyspnea, since there was no complete central airway occlusion.…”

Section: Discussionmentioning

confidence: 81%

A Rare Cause of Cough: Tracheobronchial Myxoid Spindle Cell Lipoma

Rodriguez

Weil

Ramírez³

2020

Case Reports in Pulmonology

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Background. Endobronchial lipomas are a particularly rare form of benign lung neoplasms, with an incidence of 0.1-0.4%. They are often clinically silent, though present with nonspecific symptoms that can result in extensive workup or significant delay prior to diagnosis, as presented in this case. Case Presentation. A 61-year-old male presented with chronic productive cough and occasional dyspnea and a 10-year history of clinically diagnosis of intermittent, exercise-induced asthma, nonresponsive to bronchodilators, and with normal pulmonary function tests. A chest ray showed a band-like opacity in the right middle lobe of the lung and a CT of the chest showed right lung atelectasis with a soft tissue mass in the right main bronchus. The patient underwent bronchoscopy with biopsy, which demonstrated an endobronchial myxoid spindle cell lipoma. The lesion was subsequently removed by a bronchoscopic snare. The patient’s asthmatic-like symptomatology resolved after the mass was excised. Conclusion. Though rare, endobronchial lipomas characteristically present with nonspecific signs and symptoms and thus can be easily mistaken for other medical conditions, delaying diagnosis and prolonging symptoms.

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“…With the development of bronchoscopic interventional technology, bronchoscopic interventional therapy for benign central airway stenosis has been widely used [ 2 , 4 , 12 , 15 ]. When compared with surgery, bronchoscopic resection can completely relieve the symptoms of patients, has a low risk, fewer complications, better patient tolerance, and would preserve lung tissue and lung function [ 2 , 20 ]. Most cases of proximal endobronchial lipoma can be removed by bronchoscopy.…”

Section: Discussionmentioning

confidence: 99%

Multiple endo bronchial lipoma: a rare case report

Zhao¹,

Shui²,

Dai³

2020

BMC Pulm Med

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Background Endobronchial lipoma is an extremely rare benign tumor, which is generally located in the first three subdivisions of the tracheobronchial tree. According to the existing literature, all endobronchial lipomas are single (one per patient). Here, we report a rare case in which the patient presented with two endobronchial lipomas in the same patient, and underwent a bronchoscopic tumor resection in the left main bronchus and the left lower bronchus. Both tumors were pathologically confirmed as endobronchial lipoma. Case presentation A 52-year-old Chinese man presented at the clinic reporting a mild cough with yellow color sputum and exertional dyspnea for 2 weeks. He was a heavy smoker (45 pack-years). Chest auscultation demonstrated faint wheezing in left lower lobe. Computed tomography (CT) revealed two low-density endobronchial masses located in the middle segment of the left main bronchus and the posterior basilar segmental bronchus of the left lower lobe. The neoplasms measured a CT-attenuation value of -70HU, −98HU in density with air trapping and atelectasis in the segmental bronchus of the left lower lobe. The patient underwent interventional bronchoscopic management to remove the neoplasms by using an electrosurgical snare, cryotherapy, and electrocautery. The locations of the neoplasms were confirmed at the left main bronchus and the superior segment of the left lower lobe during bronchoscopic intervention. Histopathological examination confirmed that both tissues were consistent with lipomas. After 18 months of follow-up, the patient was free of symptoms and CT revealed that bronchiectasia remained in the superior segment of the left lower lobe; however, no mass lesion was present in the left bronchus. Conclusions This case suggests that an endobronchial lipoma can present as multiple lesions, and both proximal and distal types can simultaneously occur in the same patient. Thus, these findings help us further understand the biology of endobronchial lipomas.

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Endobronchial Lipoma

Cited by 5 publications

References 5 publications

Endobronchial Lipoma: A Rare Cause of Bronchial Stenosis or Obstruction

Endobronchial Lipoma: A Rare Cause of Bronchial Stenosis or Obstruction

A Rare Cause of Cough: Tracheobronchial Myxoid Spindle Cell Lipoma

Multiple endo bronchial lipoma: a rare case report

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