Encephalopathy: an unusual neurologic complication of autologous hematopoietic stem cell transplant in patients with multiple myeloma with renal failure

Akı, Şahika Zeynep; Pamukçuoğlu, Merve; Bagriacik, Umit Emin; Sucak, Gülsan Türköz

doi:10.3109/10428194.2012.721545

Cited by 3 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…55,56 Most neurologic complications occur within 100 days of transplant and manifest as seizure and encephalopathy. Seizures are most common immediately after the stem cell infusion and may be related to dimethyl sulfoxide used for cryopreservation.…”

Section: Confusion: Indirect Relation To Cancer Treatmentmentioning

confidence: 99%

The confused oncologic patient: a rational clinical approach

Nolan

DeAngelis

2016

Current Opinion in Neurology

View full text Add to dashboard Cite

Purpose of review The purpose of this review is to provide a practical clinical approach to confusion in the patient with cancer. Confusion in the cancer population has a broader differential diagnosis than in the general medical population. The clinician must consider the usual differential diagnoses as well as causes unique to the cancer patient including direct complications from the cancer and indirect complications related to cancer treatment. Recent findings In the recent age of precision medicine, the oncologist now utilizes the genomic profile of both the patient and the tumor to provide advanced biologic therapies including targeted anticancer drugs, antiangiogenic agents, and immunotherapy. Such advances carry with them an emerging pattern of neurotoxicity which, although less well described in the literature, is now an important consideration to the clinical approach to confusion in cancer patients. Summary Confusion is the most common neurologic complication in cancer and is associated with significant morbidity, mortality, and prolonged hospital stays resulting in increased health care costs. Early recognition and treatment of delirium is essential to improve clinical outcomes.

show abstract

Section: Confusion: Indirect Relation To Cancer Treatmentmentioning

confidence: 99%

The confused oncologic patient: a rational clinical approach

Nolan

DeAngelis

2016

Current Opinion in Neurology

View full text Add to dashboard Cite

show abstract

“…Spinal cord compression, leptomemingeal involvement, intracranial plasmacytomas, and cranial palsies induced by electrolyte and metabolic derangements are among other neurological manifestations of MM [1]. Moreover anti-myeloma treatment might as well lead to emergence and/or exacerbation of the existing neuropathy.…”

Section: Introductionmentioning

confidence: 99%

A Patient with Multiple Myeloma who Developed Severe Myoclonus after Stem Cell Transplantation

Güner¹,

PamukçuoÃÂlu²

2015

J Leuk

View full text Add to dashboard Cite

There are various neurologic manifestations of Multiple Myeloma (MM) seen either at presentation or as a complication of various anti-myeloma agents administered during the course of the disease. These neurologic complications might occasionally be challenging to diagnose and treat. Peripheral nervous system is more commonly affected and peripheral neuropathy is the most common form of neurologic complications seen in MM. Here we report a gentleman with MM on regular renal replacement therapy developed severe myoclonus 3 days status post autologous stem cell (ASCT). Besides MM, he had Hypertension and Diabetes Mellitus as to his renal failure. He was also suffering from neuropathy for which gabapentin was commenced.

show abstract

Fentanyl/melphalan

2013

Reactions Weekly

View full text Add to dashboard Cite

Encephalopathy: an unusual neurologic complication of autologous hematopoietic stem cell transplant in patients with multiple myeloma with renal failure

Cited by 3 publications

References 12 publications

The confused oncologic patient: a rational clinical approach

The confused oncologic patient: a rational clinical approach

A Patient with Multiple Myeloma who Developed Severe Myoclonus after Stem Cell Transplantation

Fentanyl/melphalan

Contact Info

Product

Resources

About