Encapsulation of Mānuka Essential Oil in Yeast Microcarriers for Enhanced Thermal Stability and Antimicrobial activity

Liu, Shanshan; Tao, Meihan; Huang, Kuan-Chun

doi:10.1007/s11947-021-02714-y

Cited by 16 publications

(10 citation statements)

References 48 publications

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“…In general, it has been reported that the presence of rich β-triketones offers a high level of antimicrobial activity against Gram-positive organisms, such as Staphylococcus spp., Enterococcus spp., and Streptococcus spp., as well as certain dermatophytic fungi [ 21 , 22 ]. In addition, the leptospermone of the β-triketone chemotype isolated from L. scoparium is known to exhibit unique and strong antimicrobial properties [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

Enhancement of Biofunctionalization by Loading Manuka Oil on TiO2 Nanotubes

Kim

Jang

et al. 2022

Nanomaterials

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Metallic implants (mesh) for guided bone regeneration can result in foreign body reactions with surrounding tissues, infection, and inflammatory reactions caused by micro-organisms in the oral cavity after implantation. This study aimed to reduce the possibility of surgical failure caused by microbial infection by loading antibacterial manuka oil in a biocompatible nanostructure surface on Ti and to induce stable bone regeneration in the bone defect. The manuka oil from New Zealand consisted of a rich β-triketone chemotype, leptospermone, which showed strong inhibitory effects against several bacteria, even at very low oil concentrations. The TiO2 nanotubular layer formed by anodization effectively enhanced the surface hydrophilicity, bioactivity, and fast initial bone regeneration. A concentration of manuka oil in the range of 0.02% to less than 1% can have a synergistic effect on antibacterial activity and excellent biocompatibility. A manuka oil coating (especially with a concentration of 0.5%) on the TiO2 nanotube layer can be expected not only to prevent stenosis of the connective tissue around the mesh and inflammation by microbial infection but also to be effective in stable and rapid bone regeneration.

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Section: Discussionmentioning

confidence: 99%

Enhancement of Biofunctionalization by Loading Manuka Oil on TiO2 Nanotubes

Kim

Jang

et al. 2022

Nanomaterials

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“…To prove the absence of spores, the culture was heated at 80 °C for 10 min and spread on TSA plates. After overnight incubation, there was no colony growth, and no spores were observed in the culture by a microscope, indicating that there were no spores in the initial bacterial culture [ 33 ].…”

Section: Methodsmentioning

confidence: 99%

Effect of Temperature, pH, and aw on Cereulide Synthesis and Regulator Genes Transcription with Respect to Bacillus cereus Growth and Cereulide Production

Wang,

Liu,

Yang

et al. 2024

Toxins

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Bacillus cereus is a food-borne pathogen that can produce cereulide in the growth period, which causes food poisoning symptoms. Due to its resistance to heat, extreme pH, and proteolytic enzymes, cereulide poses a serious threat to food safety. Temperature, pH, and aw can influence cereulide production, but there is still a lack of research with multi-environmental impacts. In this study, the effects of temperature (15~45 °C), pH (5~8), and aw (0.945~0.996) on the emetic reference strain B. cereus F4810/72 growth, cereulide production, relevant ces genes (cesA, cesB, cesP), and transcription regulators genes (codY and abrB) expression at transcription level were studied. B. cereus survived for 4~53 h or grew to 6.85~8.15 log10 CFU/mL in environmental combinations. Cereulide accumulation was higher in mid-temperature, acidic, or high aw environments. Increased temperature resulted in a lower cereulide concentration at pH 8 or aw of 0.970. The lowest cereulide concentration was found at pH 6.5 with an increased aw from 0.970 to 0.996. Water activity had a strong effect on transcriptional regulator genes as well as the cesB gene, and temperature was the main effect factor of cesP gene expression. Moreover, environmental factors also impact cereulide synthesis at transcriptional levels thereby altering the cereulide concentrations. The interaction of environmental factors may result in the survival of B. cereus without growth for a period. Gene expression is affected by environmental factors, and temperature and pH may be the main factors influencing the correlation between B. cereus growth and cereulide formation. This study contributed to an initial understanding of the intrinsic link between the impact of environmental factors and cereulide formation and provided valuable information for clarifying the mechanism of cereulide synthesis in combined environmental conditions.

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“…However, when it was encapsulated, the MBC not only was the same for all the bacteria tested but also decreased down to 2.5 mg/ml in all the cases (Amani et al, 2021). Advantages of encapsulation were proven in Liu et al (2021); antimicrobial activity of Mānuka EO (MEO) was improved encapsulating it into yeast cells by reducing three times the bacterial population during the same time (1 hour). An interesting conclusion of this study is that encapsulation boosted MEO antibacterial properties in an organic-rich environment.…”

Section: Natural Antimicrobial Compoundsmentioning

confidence: 99%

“…An interesting conclusion of this study is that encapsulation boosted MEO antibacterial properties in an organic-rich environment. This shows that a controlled release prevents non-specific reactions of the bioactive compound that would be consumed by organic matter in the surroundings undesirably, worsening its antimicrobial activity (Liu et al, 2021).…”

Section: Natural Antimicrobial Compoundsmentioning

confidence: 99%

Sustainable antibiofilm self-assembled colloidal systems

Morán

Saweres-Argüelles²,

Marchianò³

et al. 2022

Front. Soft. Matter

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Biofilms find a favorable environment in industrial processes such as food, cosmetic, or medical prosthesis and devices, being responsible of approximately 80% of human bacterial infections. Prevention and/or eradication of microorganism’ films is a worldwide need. There is an increasing interest on the finding and use of novel antimicrobial compounds without side effects. An additional challenge is to fight the antimicrobial resistance that some bacteria and microorganisms develop with traditional antibiotics. Also, in recent years, sustainability and natural source of the antibiofilm chemical principles are also a priority demand. Colloidal systems such as vesicles, particle suspensions, or emulsions are becoming increasingly useful tools for biocompound delivery due to their ability to protect the compound encapsulated against external factors and their possibility to be used as target delivery systems. During the last decade, these types of systems have been widely used for the encapsulation of traditional and novel compounds with antimicrobial properties. The present study summarizes different types of natural compounds tested against several types of bacteria and their feasibility to be encapsulated in different types of colloidal systems.

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Encapsulation of Mānuka Essential Oil in Yeast Microcarriers for Enhanced Thermal Stability and Antimicrobial activity

Cited by 16 publications

References 48 publications

Enhancement of Biofunctionalization by Loading Manuka Oil on TiO2 Nanotubes

Enhancement of Biofunctionalization by Loading Manuka Oil on TiO2 Nanotubes

Effect of Temperature, pH, and aw on Cereulide Synthesis and Regulator Genes Transcription with Respect to Bacillus cereus Growth and Cereulide Production

Sustainable antibiofilm self-assembled colloidal systems

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