Enamel Matrix Derivative and Coronal Flaps to Cover Marginal Tissue Recessions

Castellanos, T Adriana; Rosa, R. M. De La; Garza, Myriam de la; Caffesse, Raúl G.

doi:10.1902/jop.2006.77.1.7

Cited by 90 publications

(144 citation statements)

References 44 publications

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“…The test sites demonstrated better root coverage (92.9% after 6 months) compared to the control sites (66.8% after 6 months) [132] . These results were recently corroborated by others [133] . In a controlled, clinical, split-mouth study involving 17 patients, the therapy of buccal Miller class II recessions with a coronally positioned flap and EMD (test group) or flap alone was compared to connective tissue graft (control) [134] .…”

Section: Controlled Clinical Studies In Recession Defectssupporting

confidence: 84%

The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

et al. 2007

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Regenerative periodontal therapy aims at reconstitution of the lost periodontal structures such as new formation of root cementum, periodontal ligament and alveolar bone. Findings from basic research indicate that enamel matrix protein derivative (EMD) has a key role in periodontal wound healing. Histological results from animal and human studies have shown that treatment with EMD promotes periodontal regeneration. Moreover, clinical studies have indicated that treatment with EMD positively influences periodontal wound healing in humans. This review aims to present an overview of evidence-based clinical indications for regenerative therapy with EMD.

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Section: Controlled Clinical Studies In Recession Defectssupporting

confidence: 84%

The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

et al. 2007

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“…These findings are within the range reported by Castellanos et al . (2006)[11] and Prato et al . (2000),[12] where they found 88.6% and 62.2% of root coverage in patients treated with EMD+CPF and CPF alone, respectively, after 12 months.…”

Section: Discussionmentioning

confidence: 99%

The effectiveness of enamel matrix protein (Emdogain^® ) in combination with coronally advanced flap in the treatment of multiple marginal tissue recession: A clinical study

Jaiswal¹,

Kumar²,

Khatri³

et al. 2012

J Indian Soc Periodontol

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Background:Gingival recession resulting in root exposure is a common problem faced by clinicians. This clinical study compared the results obtained by treating gingival recession using enamel matrix derivative (Emdogain gel®) along with coronally positioned flap and coronally positioned flap alone.Materials and Methods:Twenty patients with a total of 46 gingival recession defects, each patient with a minimum of two recession defects, were included in the study. The test group, which consisted of 10 patients with 22 recession defects, was treated by enamel matrix derivatives (Emdogain gel) in combination with a coronally positioned flap, while the control group, which consisted of 10 patients with 24 gingival recession defects, was treated with 24% ethylenediaminetetraacetic acid (EDTA; Prefgel®) in combination with coronally positioned flap.Results:Student's paired and unpaired t-test was used for statistical analysis. If the probability value (P) was less than 0.05, it was considered significant. Data from this study demonstrated that application of (EMD) Emdogain gel resulted in a statistically significant increase in root coverage, gain in the clinical attachment level (CAL), and probing pocket depth (PPD) reduction when compared with coronally advanced flap (CAF) alone, but there was no statistically significant difference in the width of keratinized gingiva (WKG) between the two groups.

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“…Other studies 6,7,20) involving more cases and longer follow-up periods also found no significant differences between CPF and CPF‫ם‬EMD. Meanwhile, several studies 3,5,18) have shown significantly better outcomes with CPF‫ם‬EMD than with CPF in terms of percentage of root coverage, keratinized gingival gain, and attachment gain, revealing substantial variability in the outcomes of long-term studies of CPF‫ם‬EMD.…”

Section: Discussionmentioning

confidence: 99%

Root Coverage Technique with Enamel Matrix Derivative

Moriyama

Matsumoto

Makiishi

2009

Bull. Tokyo Dent. Coll.

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Various periodontal plastic surgical techniques are employed in obtaining root coverage. Recently, the use of an enamel matrix derivative (EMD) has been reported in such treatment. We report 2 cases of root coverage surgery with a coronally positioned flap in combination with EMD (CPF‫ם‬EMD) and connective tissue graft in combination with EMD (CTG‫ם‬EMD). Case 1: The patient was a 25-year-old woman referred to Suidobashi Hospital, Tokyo Dental College for root coverage surgery on the lower right first premolar. Gingival recession was classified as Miller Class II, as no alveolar bone loss or loss of attachment was observed in the interdental area, although recession had progressed to the mucogingival junction. The patient was diagnosed with local gingival recession caused by excessive tooth brushing. Primary conservative treatment failed to reduce the gingival recession. Subsequently, root coverage surgery with CPF‫ם‬EMD was carried out. As observation at the 1-year follow-up revealed complete root coverage and no recurrence of root exposure or subjective symptoms, the postoperative course was considered to be favorable. Case 2: The patient was a 39-year-old woman referred to Suidobashi Hospital, Tokyo Dental College for root coverage surgery on the lower left canine. Gingival recession was classified as Miller Class II. Root coverage surgery with CTG‫ם‬EMD was carried out. As observation at the 2-month follow-up revealed complete root coverage and no recurrence of root exposure, the postoperative course was considered to be favorable. These 2 cases indicate the effectiveness of root coverage surgery with CPF‫ם‬EMD and CTG‫ם‬EMD.

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Enamel Matrix Derivative and Coronal Flaps to Cover Marginal Tissue Recessions

Abstract: The coronally positioned flap alone or with EMD is an effective procedure to cover localized gingival recessions. The addition of EMD significantly improves the amount of root coverage.

Cited by 90 publications

References 44 publications

The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

The effectiveness of enamel matrix protein (Emdogain^® ) in combination with coronally advanced flap in the treatment of multiple marginal tissue recession: A clinical study

Root Coverage Technique with Enamel Matrix Derivative

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Enamel Matrix Derivative and Coronal Flaps to Cover Marginal Tissue Recessions

Abstract: The coronally positioned flap alone or with EMD is an effective procedure to cover localized gingival recessions. The addition of EMD significantly improves the amount of root coverage.

Cited by 90 publications

References 44 publications

The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

The Application of an Enamel Matrix Protein Derivative (Emdogain®) in Regenerative Periodontal Therapy: A Review

The effectiveness of enamel matrix protein (Emdogain® ) in combination with coronally advanced flap in the treatment of multiple marginal tissue recession: A clinical study

Root Coverage Technique with Enamel Matrix Derivative

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The effectiveness of enamel matrix protein (Emdogain^® ) in combination with coronally advanced flap in the treatment of multiple marginal tissue recession: A clinical study