Enamel Based Composite Layers Deposited on Titanium Substrate with Antifungal Activity

Iconaru, Simona Liliana; Продан, А. М.; Turculeţ, Claudiu; Beuran, Mircea; Ghita, R. V.; Costescu, A.; Groza, Andreea; Chifiriuc, Mariana Carmen; Chapon, Patrick; Gaiaschi, Sofia; Hristu, Radu; Stanciu, G.; Trușcă, Roxana; Ganciu, M.; Raita, Stefania; Vineticu, N.; Ciobanu, Carmen Steluţa

doi:10.1155/2016/4361051

Cited by 20 publications

(22 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The antifungal properties of the HApAg5 and HApAg20 suspensions and thin layers were determined using a common reference strain of fungi, Candida albicans from the American Type Culture Collection (ATCC, Old Town Manassas, Virginia, USA), Candida albicans ATCC 10231. The assessment of the antifungal properties of the samples were performed using fungal suspensions of a known density (~1.5 × 10 5 -10 6 colony forming units (CFU)/mL), obtained from 15 to 18 h fungal cultures as reported in Iconaru et al [28]. The fungal biofilm development on the surface HApAg5 and HApAg20 thin layers was qualitatively investigated by scanning electron microscopy (SEM).…”

Section: In Vitro Antifungal Assaysmentioning

confidence: 99%

Silver-Doped Hydroxyapatite Thin Layers Obtained by Sol-Gel Spin Coating Procedure

et al. 2019

View full text Add to dashboard Cite

The main objective of this paper is to develop silver-doped hydroxyapatite suspensions (HApAg) with different concentrations of silver (?Ag = 0.05 and ?Ag = 0.2) in order to obtain uniform and homogenous layers by spin-coating procedure. The colloidal properties of HApAg suspensions are evaluated by dynamic light scattering (DLS) analysis, ζ-potential (ZP), and ultrasound measurements. The ultrasound studies show that the HApAg20 sample revealed better stability than the HApAg5 sample. The structural and morphological analysis on suspensions and thin layers is also conducted. It is observed that the particles of the two samples have a similar shape and are uniform. The layers obtained present a homogeneous appearance of the surface without evidence of cracks or interruption of the coatings. The in vitro antifungal studies conducted on the two thin layers at two different time intervals (24 and 48 h) show that both HApAg5 (?Ag = 0.05) and HApAg20 (?Ag = 0.05) nanoparticles suspensions and composite layers inhibit the development of colony forming units (CFU) even after 24 h of incubation comparative to the control, represented by the Candida albicans (C. albicans) culture in a proper medium. The fungicidal effect was evident after 48 h of incubation in the case of both HApAg20 nanoparticles suspensions and composite layers.

show abstract

Section: In Vitro Antifungal Assaysmentioning

confidence: 99%

Silver-Doped Hydroxyapatite Thin Layers Obtained by Sol-Gel Spin Coating Procedure

et al. 2019

View full text Add to dashboard Cite

show abstract

“…During recent years, constant efforts have been made in developing bioceramic materials and enhancing their mechanical and biological properties for use in biomedical applications [1][2][3][4][5]. Due to their properties, bioceramic materials are usually used for developing bone substitutes both in medical and dental applications.…”

Section: Introductionmentioning

confidence: 99%

“…Due to their properties, bioceramic materials are usually used for developing bone substitutes both in medical and dental applications. The primary uses of calcium phosphate ceramics and calcium phosphate-based composites in dental and medical applications consists in the repair of periodontal defects and dental bone repair as well as in the augmentation of alveolar ridge, dental implants, ear implants, tissue engineering for dental bone grafts, spine fusion and adjuvant to uncoated implants [3][4][5][6]. The need for material based on hydroxyapatite with better mechanical, structural, and biological properties.…”

Section: Introductionmentioning

confidence: 99%

Obtaining and Characterizing Thin Layers of Magnesium Doped Hydroxyapatite by Dip Coating Procedure

et al. 2020

View full text Add to dashboard Cite

A simple dip coating procedure was used to prepare the magnesium doped hydroxyapatite coatings. An adapted co-precipitation method was used in order to obtain a Ca25−xMgx(PO4)6(OH)2, 25MgHAp (xMg = 0.25) suspension for preparing the coatings. The stabilities of 25MgHAp suspensions were evaluated using ultrasound measurements, zeta potential (ZP), and dynamic light scattering (DLS). Using transmission electron microscopy (TEM) and scanning electron microscopy (SEM) information at nanometric resolution regarding the shape and distribution of the 25MgHAp particles in suspension was obtained. The surfaces of obtained layers were evaluated using SEM and atomic force microscopy (AFM) analysis. The antimicrobial evaluation of 25MgHAp suspensions and coatings on various bacterial strains and fungus were realized. The present study presents important results regarding the physico-chemical and antimicrobial studies of the magnesium doped hydroxyapatite suspensions, as well as the coatings. The studies have shown that magnesium doped hydroxyapatite suspensions prepared with xMg = 0.25 presented a good stability and relevant antimicrobial properties. The coatings made using 25MgHAp suspension were homogeneous and showed remarkable antimicrobial properties. Also, it was observed that the layer realized has antimicrobial properties very close to those of the suspension. Both samples of the 25MgHAp suspensions and coatings have very good biocompatible properties.

show abstract

“…With the general chemical formula, Ca 10 (PO 4 ) 6 (OH) 2 , HAp is a bioactive bioceramic belonging to the apatite family and is chemically similar to the mineral component of hard tissues found in mammals [ 1 , 2 ]. Therefore, due to its outstanding biological and physico-chemical properties, HAp, is widely used in biomedical applications for hard tissue replacements, scaffolds, as coating for implantable devices, and as a reinforcement material in biocomposites [ 3 , 4 , 5 , 6 ]. Despite its numerous properties, some drawbacks of HAp such as slow growth rate and the predilection of facilitating bacterial adherence and proliferation have been identified [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Development of Zinc-Doped Hydroxyapatite by Sol-Gel Method for Medical Applications

et al. 2018

View full text Add to dashboard Cite

Zinc- (Zn) doped hydroxyapatite (HAp) were prepared by sol-gel method. Zinc-doped hydroxyapatite (ZnHAp) and HAp were analyzed by X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The Rietveld analysis revealed that the HAp and 7ZnHAp powders obtained by sol-gel method have a monophasic hydroxyapatite structure belonging to the P63/m spatial group. The results obtained from the ultrasound characterization of HAp and ZnHAp are also presented in this study. The effect of zinc concentration on properties that were deduced from ultrasonic measurements are studied in the case of a significant zinc concentration (xZn = 0.07). From the values of the ultrasonic waves velocities were determined by the pairs of elastic coefficients of the suspensions (Young modulus E, Poisson coefficient ν), which have proven to be similar to those determined by other authors.

show abstract

Enamel Based Composite Layers Deposited on Titanium Substrate with Antifungal Activity

Cited by 20 publications

References 46 publications

Silver-Doped Hydroxyapatite Thin Layers Obtained by Sol-Gel Spin Coating Procedure

Silver-Doped Hydroxyapatite Thin Layers Obtained by Sol-Gel Spin Coating Procedure

Obtaining and Characterizing Thin Layers of Magnesium Doped Hydroxyapatite by Dip Coating Procedure

Development of Zinc-Doped Hydroxyapatite by Sol-Gel Method for Medical Applications

Contact Info

Product

Resources

About