En-face Optical Coherence Tomography as a Novel Tool for Exploring the Ocular Surface: A Pilot Comparative Study to Conventional B-Scans and in Vivo Confocal Microscopy

Hassani, Rachid Tahiri Joutei; Liang, Hong; Sanharawi, Mohamed El; Brasnu, Emmanuelle; Kallel, Sofiene; Labbé, Antoine; Baudouin, Christophe

doi:10.1016/j.jtos.2014.02.006

Cited by 19 publications

(11 citation statements)

References 53 publications

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“…AS-OCT examination proved to be a very informative tool in the diagnosis of conjunctival nevi [ 7 ]. 3D volume scans can be analysed both cross-sectionally (B scans) and in the frontal plane, that is, perpendicular to the visual axis and so-called “en face” (C scans) [ 8 ]. B scan images can detect cysts in the cross-sectional scans, while intralesional vessel morphology can be exactly depicted on C scans allowing precise follow-up of intralesional vascularity.…”

Section: Discussionmentioning

confidence: 99%

Giant Conjunctival Nevus in a 12-Year-Old Child

Tóth-Molnár

Vizvári

Vörös

2017

Case Reports in Ophthalmological Medicine

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We describe a case of a giant conjunctival nevus presented in a 12-year-old girl with suspicious clinicomorphological appearance. The lesion was noticed by the parents at the age of 3 years as a “fleshy spot” on the bulbar conjunctiva. The lesion remained unchanged until approx. 6 months before recent admission. On slit-lamp examination, a large conjunctival lesion with variegate pigmentation and indistinct margins was detected on the superonasal part of the bulbar conjunctiva of the left eye. Intralesional cysts and vessels were detected with AS-OCT examination. Wide excision and cryotherapy to the scleral bed were performed and amniotic membrane graft was used to restore the ocular surface. Histopathological examination revealed compound type conjunctival nevus and disclosed any sign of malignancy. Although giant conjunctival nevus is a rare entity, precise diagnosis and adequate management are very important as it can be confused with malignant melanoma.

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Section: Discussionmentioning

confidence: 99%

Giant Conjunctival Nevus in a 12-Year-Old Child

Tóth-Molnár

Vizvári

Vörös

2017

Case Reports in Ophthalmological Medicine

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“…Visualization in a frontal plane can reveal supplemental morphological details in patients with ocular surface conditions. This may improve the quality of diagnosis and be used to monitor the efficacy of treatments with no corneal contact [18].…”

Section: Complicationsmentioning

confidence: 99%

“…It produces coronal sections (C-scans) oriented in a frontal plane, perpendicular to the optical axis of the eye. Although there are few published papers reporting the use of en face ASOCT, it was found to provide complementary information not readily available with conventional imaging techniques and new insight into different ocular surface conditions noninvasively [18].…”

Section: Introductionmentioning

confidence: 99%

Developments in Contact Lens Imaging: New Applications of Optical Coherence Tomography

et al. 2019

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Optical coherence tomography (OCT) is a high-speed and non-contact optical imaging technology widely used for noninvasive cross-sectional imaging of biological objects. Two main OCT technologies have been developed: time domain and Fourier domain technologies. The latter can be further divided into spectral domain OCT, which uses a broadband light source and a spectrometer as a detector, and swept source OCT, which employs a quickly-rotating laser source. Advances in OCT technology have made it one of the most helpful devices in ophthalmic practice. Fourier OCT has revolutionized imaging of the posterior segment of the eye, as well as of anterior structures and has enhanced the ability to diagnose and manage patients. It provides high-resolution information about the tear film, contact lens (CL), a qualitative and quantitative assessment of the anterior eye that is important in contact lens fitting, and allows possible eye surface changes while wearing contact lenses to be monitored. Potential swept source OCT technology applications include industrial processes of lens design and quality control. In this paper, we describe clinical applications and outline a variety of multifunctional uses of OCT in the field of refractive error correction with contact lenses.

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“…En face OCT can visualize ocular surface changes that are not detectable using conventional B-scan OCT in patients with corneal dystrophies, keratitis, pterygium, conjunctivochalasis, or OSSN [ 53 ]. Although its resolution is lower than that of in vivo confocal microscopy, it allows overall visualization of the lesions due to the larger scan width [ 53 ]. Compared with in vivo confocal microscopy, en face OCT is also advantageous because it is a noncontact method that allows easy and rapid image capture [ 53 ].…”

Section: As-oct For Diagnosis Of Corneal and Anterior Segment Disementioning

confidence: 99%

“…Although its resolution is lower than that of in vivo confocal microscopy, it allows overall visualization of the lesions due to the larger scan width [ 53 ]. Compared with in vivo confocal microscopy, en face OCT is also advantageous because it is a noncontact method that allows easy and rapid image capture [ 53 ].…”

Section: As-oct For Diagnosis Of Corneal and Anterior Segment Disementioning

confidence: 99%

Applications of Anterior Segment Optical Coherence Tomography in Cornea and Ocular Surface Diseases

Han

Liu

Mohamed-Noriega

et al. 2016

Journal of Ophthalmology

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Optical coherence tomography (OCT) is a noncontact technology that produces high-resolution cross-sectional images of ocular tissues. Anterior segment OCT (AS-OCT) enables the precise visualization of anterior segment structure; thus, it can be used in various corneal and ocular surface disorders. In this review, the authors will discuss the application of AS-OCT for diagnosis and management of various corneal and ocular surface disorders. Use of AS-OCT for anterior segment surgery and postoperative management will also be discussed. In addition, application of the device for research using human data and animal models will be introduced.

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En-face Optical Coherence Tomography as a Novel Tool for Exploring the Ocular Surface: A Pilot Comparative Study to Conventional B-Scans and in Vivo Confocal Microscopy

Cited by 19 publications

References 53 publications

Giant Conjunctival Nevus in a 12-Year-Old Child

Giant Conjunctival Nevus in a 12-Year-Old Child

Developments in Contact Lens Imaging: New Applications of Optical Coherence Tomography

Applications of Anterior Segment Optical Coherence Tomography in Cornea and Ocular Surface Diseases

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