Employment of targeted nanoparticles for imaging of cellular processes in cardiovascular disease

Modak, Mallika; Frey, Molly; Yi, Sijia; Liu, Yugang; Scott, Evan A.

doi:10.1016/j.copbio.2020.06.003

Cited by 15 publications

(7 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Green-synthesized nanoparticles have been used successfully in human health issues, which included many approaches like solving, treatment and preventing these problems ( Nkanga and Steinmetz, 2021 , Paiva-Santos et al, 2021 ). The green metal-NPs have several applications as antimicrobial agents ( Banasiuk et al, 2020 ), in cellular imaging, as catalysts ( Modak et al, 2020 ), for remediation of environmental pollutants ( Bhavya et al, 2021 , Orooji et al, 2021 ), as alternative energy source, as sensors ( Zamarchi and Vieira, 2021 ) and as anti-microfouling agents ( Rana et al, 2020 ). Many green synthesis nanoparticles have been applied for multifaceted applications for human health such as antimicrobial agents ( Sharma et al, 2021 ) as reported for nanoparticles of MgO-NPs ( Vidhya et al, 2021 ), Zn-NPs and Ag-NPs ( Munir et al, 2020 ), and ZnO-NPs ( Umavathi et al, 2021 ).…”

Section: Nutrients Based Nanoparticles In Edible Plants For Human Healthmentioning

confidence: 99%

Nano-biofortification of different crops to immune against COVID-19: A review

El-Ramady

Abdalla

Elbasiouny

et al. 2021

Ecotoxicology and Environmental Safety

View full text Add to dashboard Cite

Human health and its improvement are the main target of several studies related to medical, agricultural and industrial sciences. The human health is the primary conclusion of many studies. The improving of human health may include supplying the people with enough and safe nutrients against malnutrition to fight against multiple diseases like COVID-19. Biofortification is a process by which the edible plants can be enriched with essential nutrients for human health against malnutrition. After the great success of biofortification approach in the human struggle against malnutrition, a new biotechnological tool in enriching the crops with essential nutrients in the form of nanoparticles to supplement human diet with balanced diet is called nano-biofortification. Nano biofortification can be achieved by applying the nano particles of essential nutrients (e.g., Cu, Fe, Se and Zn) foliar or their nano-fertilizers in soils or waters. Not all essential nutrients for human nutrition can be biofortified in the nano-form using all edible plants but there are several obstacles prevent this approach. These stumbling blocks are increased due to COVID-19 and its problems including the global trade, global breakdown between countries, and global crisis of food production. The main target of this review was to evaluate the nano-biofortification process and its using against malnutrition as a new approach in the era of COVID-19. This review also opens many questions, which are needed to be answered like is nano-biofortification a promising solution against malnutrition? Is COVID-19 will increase the global crisis of malnutrition? What is the best method of applied nano-nutrients to achieve nano-biofortification? What are the challenges of nano-biofortification during and post of the COVID-19?

show abstract

Section: Nutrients Based Nanoparticles In Edible Plants For Human Healthmentioning

confidence: 99%

Nano-biofortification of different crops to immune against COVID-19: A review

El-Ramady

Abdalla

Elbasiouny

et al. 2021

Ecotoxicology and Environmental Safety

View full text Add to dashboard Cite

show abstract

“…Although nanomedicine techniques are only beginning to be recognized in cardiovascular therapy, many studies have already generated some promising results, with mainstream research focusing on the design of nanocarriers to improve drug delivery and thereby treatment outcomes [ 9 , 10 , 11 , 12 , 13 , 14 ]. Several studies have demonstrated that delivering drugs to heart tissues, cells, and molecules through nanocarriers can significantly increase oral availability and half-life, reduce side effects, and optimize therapeutic outcomes [ 15 , 16 , 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Nanoparticles in the New Era of Cardiovascular Therapeutics: Challenges and Opportunities

Yang

Ren

Yang

2023

IJMS

View full text Add to dashboard Cite

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Although a cadre of therapeutic strategies have been made available for CVDs in the clinical setting, predominantly through medication and surgery, these do not fully address the clinical needs of patients with CVD. As a new technique for CVD treatment, nanocarriers are employed to modify and package medications to ease the targeting of tissues, cells and molecules within the cardiovascular system. Nanocarriers are made of biomaterials, metals, or a combination of these materials, with sizes similar to bioactive molecules such as proteins and DNA. Cardiovascular nanomedicine (CVN) has only surfaced in recent years and is still in its infancy. Ample studies have displayed promise for the clinical utility of nanomedicine techniques, courtesy of continued perfection in nanocarrier design to optimize drug delivery and treatment outcomes. Here in this review, we will summarize the research advances in the literature on nanoparticles in the management of CVDs, including ischemic and coronary heart disease (e.g., atherosclerosis, angina pectoris and myocardial infarction), myocardial ischemia-reperfusion injury, aortic aneurysm, myocarditis, hypertension, and pulmonary artery hypertension and thrombosis.

show abstract

“…[ 4 , 5 ] Molecular imaging has potential utility in certain cardiovascular imaging fields, including acoustic imaging, positron emission tomography and magnetic resonance imaging. [ 6 , 7 ] While these imaging modes can function independently, they are often used in combination. Such multimodal imaging approach integrates the advantages of each technique.…”

Section: Introductionmentioning

confidence: 99%

Mapping research performance and hotspots on nanoparticles in cardiovascular diseases

Yin

Xiang

2023

Medicine

View full text Add to dashboard Cite

Nanoparticles have broad prospects and profound academic significance in cardiovascular diseases. This study aimed to comprehensively summarize the global scientific achievements of nanoparticles in cardiovascular diseases research. Articles on the application of nanoparticles in cardiovascular diseases published from 2002 to 2021 were retrieved from the science citation index expanded of the Web of Science Core Collection, and knowledge maps were generated by Cite Space, VOS viewer, and Hist Cite for further bibliometric analysis. A total of 4321 records were retrieved, and only reviews and articles were retained with a total of 4258 studies. The number of publications on nanoparticles in the cardiovascular field has steadily increased from 2002 to 2021. China and the US contribute the most to this field, producing nearly all the most influential authors and institutions in the top 10 list. The Chinese Academy of Medical Sciences and Harvard University have obtained many high-quality research results. Targeted drug delivery via nanoparticles, myocardial infarction and atherosclerosis are research hotspots. This is the first time to analyze the application of nanoparticles in the cardiovascular field by using multiple bibliometric software. This study provides evidence for researchers to understand the hotspots and directions in this area.

show abstract

Employment of targeted nanoparticles for imaging of cellular processes in cardiovascular disease

Cited by 15 publications

References 49 publications

Nano-biofortification of different crops to immune against COVID-19: A review

Nano-biofortification of different crops to immune against COVID-19: A review

Nanoparticles in the New Era of Cardiovascular Therapeutics: Challenges and Opportunities

Mapping research performance and hotspots on nanoparticles in cardiovascular diseases

Contact Info

Product

Resources

About