Emerging pharma residue contaminants: Occurrence, monitoring, risk and fate assessment – A challenge to water resource management

Sundararaman, S.; Kumar, Jatish; Prabu, D.; Devarajan, Yuvarajan

doi:10.1016/j.scitotenv.2022.153897

Cited by 40 publications

(12 citation statements)

References 113 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There are different methods for the removal of pharmaceutical compounds from wastewaters; however, due to the hydrophilicity, persistent nature, and low concentration in wastewaters, the removal of these chemicals in conventional wastewaters treatment plants is much more laborious than the removal of other organic matter and nutrients. Some processes result in primary and tertiary sludge with high concentrations of micropollutants [ 13 ], which need managing by using other types of treatments, such as incineration or plasma melting, which considerably increases treatment costs [ 14 ]. In addition, oxidation processes can produce antibiotic degradation intermediates that are toxic and carcinogenic [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Impact of Antibiotics as Waste, Physical, Chemical, and Enzymatical Degradation: Use of Laccases

et al. 2022

View full text Add to dashboard Cite

The first traces of Tetracycline (TE) were detected in human skeletons from Sudan and Egypt, finding that it may be related to the diet of the time, the use of some dyes, and the use of soils loaded with microorganisms, such as Streptomyces spp., among other microorganisms capable of producing antibiotics. However, most people only recognise authors dating between 1904 and 1940, such as Ehrlich, Domagk, and Fleming. Antibiotics are the therapeutic option for countless infections treatment; unfortunately, they are the second most common group of drugs in wastewaters worldwide due to failures in industrial waste treatments (pharmaceutics, hospitals, senior residences) and their irrational use in humans and animals. The main antibiotics problem lies in delivered and non-prescribed human use, use in livestock as growth promoters, and crop cultivation as biocides (regulated activities that have not complied in some places). This practice has led to the toxicity of the environment as antibiotics generate eutrophication, water pollution, nutrient imbalance, and press antibiotic resistance. In addition, the removal of antibiotics is not a required process in global wastewater treatment standards. This review aims to raise awareness of the negative impact of antibiotics as residues and physical, chemical, and biological treatments for their degradation. We discuss the high cost of physical and chemical treatments, the risk of using chemicals that worsen the situation, and the fact that each antibiotic class can be transformed differently with each of these treatments and generate new compounds that could be more toxic than the original ones; also, we discuss the use of enzymes for antibiotic degradation, with emphasis on laccases.

show abstract

Section: Introductionmentioning

confidence: 99%

Impact of Antibiotics as Waste, Physical, Chemical, and Enzymatical Degradation: Use of Laccases

et al. 2022

View full text Add to dashboard Cite

show abstract

“…After administration, unaltered drugs and their metabolites can also undergo further alteration in sewage due to biological, chemical, and physical processes [1,2]. Municipal wastewater treatment plants could remove microbiological organisms and biodegradable carbon, nitrogen, and phosphorus compounds but have not been built to deal with complex pharmaceutical compounds [3,4]. The soil and groundwater contamination level with drugs depends on soil properties (such as pH, organic matter content, and clay content) and physico-chemical properties of the medicines and their metabolites [5,6].…”

Section: Introductionmentioning

confidence: 99%

Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

et al. 2022

View full text Add to dashboard Cite

Nonsteroidal anti-inflammatory medications (NSAIDs) are commonly used painkillers, anti-inflammatory agents, and fever reducers. They arrive in the environment from municipal wastewater and/or agriculture waste, affecting growing plants. In our study, the impact of NSAIDs, namely, diclofenac, indomethacin, naproxen, and paracetamol, on four plant species from the Fabaceae family (Cicer arietinum, Pisum sativum, Lens culinaris, and Vicia faba) was tested. The assimilation rate and stomatal conductance decreased for all plants treated with NSAIDs. Chlorophyll and carotenoid contents in the leaves of plants under stress declined by more than 15% compared with the control plants, while the flavonoids and total phenols decreased to a lesser extent. In contrast, the plants treated with NSAIDs emit terpenes and green leaf were volatile, at a level of some nmol m−2 s−1, which could influence the atmospheric reaction and ozone formation.

show abstract

“…The presence of different pharmaceutical compounds in the environment has been the subject of several studies since they are generally polar and water-soluble molecules (Madden et al 2009). Paracetamol is widely employed worldwide for relieving pain and reducing fever or temperature in the body (Sundararaman et al 2022). The detection of these types of drugs normally occurs at low concentrations (fluctuating from μg L −1 to ng L −1 ) (Hollender et al 2008), however, long-term exposure by living organisms can cause aquatic toxicity, development of resistance in pathogenic microbes, genotoxicity, and endocrine disruption (Khetan and Collins 2007;Fessard and Le Hégarat 2010).…”

Section: Introductionmentioning

confidence: 99%

“…The detection of these types of drugs normally occurs at low concentrations (fluctuating from μg L −1 to ng L −1 ) (Hollender et al 2008), however, long-term exposure by living organisms can cause aquatic toxicity, development of resistance in pathogenic microbes, genotoxicity, and endocrine disruption (Khetan and Collins 2007;Fessard and Le Hégarat 2010). Hence a lot of studies have primarily focused on the detection of pharmaceutical contamination in various kinds of water sources like surface water, underground water, and drinking water (Sundararaman et al 2022;Jari et al 2022).…”

Section: Introductionmentioning

confidence: 99%

Adsorption of the First-Line Covid Treatment Analgesic onto Activated Carbon from Residual Pods of Erythrina Speciosa

Georgin

Franco

Netto

et al. 2022

Environmental Management

View full text Add to dashboard Cite

In this study, the residual pods of the forest species Erythrina speciosa were carbonized with ZnCl 2 to obtain porous activated carbon and investigated for the adsorptive removal of the drug paracetamol (PCM) from water. The PCM adsorption onto activated carbon is favored at acidic solution pH. The isothermal studies confirmed that increasing the temperature from 298 to 328 K decreased the adsorption capacity from 65 mg g −1 to 50.4 mg g −1 (C 0 = 175 mg L −1 ). The Freundlich model showed a better fit of the equilibrium isotherms. Thermodynamic studies confirmed the exothermic nature (ΔH 0 = −39.1066 kJ mol −1 ). Kinetic data indicates that the external mass transfer occurs in the first minutes followed by the surface diffusion, considering that the linear driving force model described the experimental data. The application of the material in the treatment of a simulated effluent with natural conditions was promising, presenting a removal of 76.45%. Therefore, it can be concluded that the application of residual pods of the forest species Erythrina speciosa carbonized with ZnCl 2 is highly efficient in the removal of the drug paracetamol and also in mixtures containing other pharmaceutical substances.

show abstract

Emerging pharma residue contaminants: Occurrence, monitoring, risk and fate assessment – A challenge to water resource management

Cited by 40 publications

References 113 publications

Impact of Antibiotics as Waste, Physical, Chemical, and Enzymatical Degradation: Use of Laccases

Impact of Antibiotics as Waste, Physical, Chemical, and Enzymatical Degradation: Use of Laccases

Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

Adsorption of the First-Line Covid Treatment Analgesic onto Activated Carbon from Residual Pods of Erythrina Speciosa

Contact Info

Product

Resources

About