Emerging Indications for Interventional Oncology: Expert Discussion on New Locoregional Treatments

Abstract

Interventional oncology (IO) employs image-guided techniques to perform minimally invasive procedures, providing lower-risk alternatives to many traditional medical and surgical therapies for cancer patients. Since its advent, due to rapidly evolving research development, its role has expanded to encompass the diagnosis and treatment of diseases across multiple body systems. In detail, interventional oncology is expanding its role across a wide spectrum of disease sites, offering a potential cure, control, or palliative care for many types of cancer patients. Due to its widespread use, a comprehensive review of the new indications for locoregional procedures is mandatory. This article summarizes the expert discussion and report from the “MIOLive Meet SIO” (Society of Interventional Oncology) session during the last MIOLive 2022 (Mediterranean Interventional Oncology Live) congress held in Rome, Italy, integrating evidence-reported literature and experience-based perceptions. The aim of this paper is to provide an updated review of the new techniques and devices available for innovative indications not only to residents and fellows but also to colleagues approaching locoregional treatments.

Single-molecule targeted therapy shrinks lung lesions and improves bone metastases: A case report

“…Finally, other interventional techniques, including spinal injections, nerve blocks, ablation (cryo-, thermo, or radiofrequency), and vertebroplasties, are available for lung cancer patients with bone metastasis, and previous research has shown good efficacy in pain control via these techniques. [29][30][31] As a case report, this study has some limitations also. First, the experience of treating a single case is not strong enough to make a generalization.…”

“…Finally, other interventional techniques, including spinal injections, nerve blocks, ablation (cryo-, thermo, or radiofrequency), and vertebroplasties, are available for lung cancer patients with bone metastasis, and previous research has shown good efficacy in pain control via these techniques. [29–31]…”

Role of Percutaneous Ablation in the Management of Intrahepatic Cholangiocarcinoma

“…In most iCCA cases, deaths are related to local disease progression rather than metastases [ 32 ]; thus, locally ablative therapies are becoming increasingly important in the management of iCCA [ 3 , 33 , 34 ]. A growing literature supports the application of percutaneous ablative therapies to iCCA; in a recent systematic review and pooled analysis upon locoregional therapies for iCCA, the results of only ablation were sufficiently consistent to allow for recommendation of use in non-surgical candidates [ 35 , 36 ]. Compared to surgical approaches, the rationale for proposing percutaneous ablation includes the fact that the technique is governed by a minimally invasive approach which is well tolerated even in patients with co-morbidities or with extensive disease related to a low overall morbidity rate.…”