Emerging breast cancer epidemic: evidence from Africa

Akarolo-Anthony, Sally; Ogundiran, Temidayo O.; Adebamowo, Clement

doi:10.1186/bcr2737

Cited by 126 publications

(131 citation statements)

References 11 publications

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“…Indeed, evidence from Africa on the emerging breast cancer epidemic in the continent shows that the current beliefs about hormone receptor subtypes of breast cancer in Africa is probably not systematically different from the pattern in other populations after adjusting for factors like age and that the reported differences are related to poor tissue handling and laboratory processing practices. 4 Overall, breast cancer (43.7%) accounted for significant proportion of breast biopsies in this study, similar to a figure of 37.2% in Maiduguri, 22 Nigeria. Of note, breast cancer is commoner than benign lesion in Nnewi 7 Nigeria, Pakistan 2 and London 23 where cancer preponderance was ascribed to selective referral of cancer cases to tertiary hospitals like ours while benign lumps are generally managed in private hospitals.…”

Section: Discussionsupporting

confidence: 84%

“…4,6 It is against this background that the usual management of a palpable breast mass is based on the assumption that the mass is cancerous until proven otherwise. 8 The need for proper evaluation of breast lumps is further emphasized by the occurrence of a subset of benign breast lesions categorized as proliferative breast diseases.…”

Section: South Eastern Nigeriamentioning

confidence: 99%

“…1,2 In recent decades, gains of life expectancy from industrialization have changed previous trends of disease in developing nations, creating a shift from diseases of pestilence and infections to those of cancers, trauma, cardiovascular disease and mental illness. 3,4 Regional heterogeneity highlights the importance of understanding local burden of diseases and setting goals and targets, taking such patterns into account. 3 Published data indicate that the rate of diagnosis of breast diseases has increased worldwide due to recent increase in awareness campaigns, greater availability of diagnostic and screening facilities and establishment of dedicated breast clinics.…”

Section: Introductionmentioning

confidence: 99%

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Clinicopathologic study of breast lumps in Abakaliki, South Eastern Nigeria

et al. 2016

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Aims and Objectives: Breast lumps are quite common, but the principal issue is differentiating malignant from the benign sub-groups. The determinants of histologic diagnosis are multifactorial, ranging from environmental, genetic to sex and age-related factors. This study aimed to document the spectrum of breast lumps in our environment. Materials and Methods: This is a descriptive prospective analysis of consecutive breast lumps biopsied at Federal Teaching Hospital Abakaliki, between December 2010 to November 2012. The data were analysed using statistical package for social sciences (SPSS) version 22.0. Results: A total of 302 patients with 359 breast lumps were seen, 298 females and 4 males giving male:Female ratio of 1:75.The ages of the patients ranged between 16-82 years with a mean of 37.0 +/-SD 13.0. Majority (56.3%) of the patients had benign lumps. Fibroadenoma was the commonest (33.8%), followed closely by invasive ductal carcinoma (32.8%), then fibrocystic change (17.2%).The occurrence of breast cancer was strongly age-related, being 1 in 5 biopsies at 20-29 years and 3 in 5 biopsies at 40-49 years age groups. Over two-third (69.0%) of 132 patients with breast cancers were premenopausal. Majority (78.8%) of the 132 patients with breast cancer presented with advanced disease. At a median follow up of 9 months,13 (9.8%) and 6(4.5%) of 132 cancer patients developed recurrences and new cancer sites respectively. Conclusion: Most patients with breast complaints present with lumps and majority are benign, fibroadenoma being the commonest histology. Occurrence of breast cancer is strongly age-related with majority of cancer patients presenting late.

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Section: Discussionsupporting

confidence: 84%

Section: South Eastern Nigeriamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Clinicopathologic study of breast lumps in Abakaliki, South Eastern Nigeria

et al. 2016

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“…[1] The estimated age standardised rate is 38.9 cases per 100 000 for the Southern Africa region, and 74.1 for the more developed world. [2] Breast cancer is the most frequent cause of cancer death among women in both the developed and developing world.…”

Section: Introductionmentioning

confidence: 99%

The effect of HIV infection on the surgical, chemo- and radiotherapy management of breast cancer. A prospective cohort study

Phakathi

Basson

Karusseit

et al. 2016

International Journal of Surgery

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“…The delayed presentation accounts for less than 10% five-year survival rate in Nigeria contrary to over 70% in western Europe and north America where more patients are diagnosed at earlier stage. [6][7][8] The recommended screening methods for early detection of breast cancer are: monthly breast self-examination (BSE), clinical breast examination (CBE) and mammography. These screening modalities exist in Nigeria but to varying degrees.…”

Section: Introductionmentioning

confidence: 99%

The prevalence of practicing breast self-examination and knowledge of breast cancer disease among women attending secondary health facility

Olaogun¹,

Emmanuel²,

Dada³

et al. 2017

Int Surg J

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Background: Early diagnosis has been shown to improve the prognosis of breast cancer, hence breast self-examination (BSE) as a screening method may have its benefits. The aim of the present study is to determine the prevalence of BSE practice, the correctness of the practice steps and the knowledge of breast cancer disease among women attending secondary health facility.Methods: The study was a descriptive study among women attending antenatal care and immunization clinics at State Specialist Hospital, Ikere-Ekiti between October and December 2015. A total of 238 women seen during the period and who consented to participate in the study were included. Structured self-administered questionnaire was used and data obtained was analyzed using SPSS version 20. Level of significance was set at P<0.05.Results: Of 238 respondents, 94.2% were between 20 and 39 years and mostly married (86.1%). Overall, 56.7% were aware of BSE mainly through health workers (44.4%) and information media (30.4%). A little above half (55.6%) practiced BSE and 24% could be adjudged to have good practice. Performing BSE was significantly related to respondents’ level of education (p=0.001) and marital status (p=0.032). There was high awareness (84%) of breast cancer but the vast majority (87%) had poor knowledge of breast cancer symptoms and signs.Conclusions: This study revealed poor quality of BSE practice and poor knowledge of breast cancer symptoms among our women despite good awareness. There is need for more health education to improve the quality of BSE practice and knowledge of breast cancer disease for early detection and treatment.

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Emerging breast cancer epidemic: evidence from Africa

Cited by 126 publications

References 11 publications

Clinicopathologic study of breast lumps in Abakaliki, South Eastern Nigeria

Clinicopathologic study of breast lumps in Abakaliki, South Eastern Nigeria

The effect of HIV infection on the surgical, chemo- and radiotherapy management of breast cancer. A prospective cohort study

The prevalence of practicing breast self-examination and knowledge of breast cancer disease among women attending secondary health facility

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