Emergence of antigenic variants of Foot-and-Mouth Disease Virus serotype O in Ecuador and preliminary evaluation of a field strain as a vaccine candidate

Maradei, Eduardo; Malirat, Viviana; Beascoechea, Claudia Perez; Espinoza, Ana Maria; Novo, Sabrina Galdo; Smitsaart, Eliana; Salgado, Gustavo; Mattion, Nora; Toledo, Jorge Rodríguez; Bergmann, I

doi:10.1016/j.vaccine.2014.02.092

Cited by 10 publications

(5 citation statements)

References 20 publications

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“…These viruses diverged in 3 lineages, of which, only one is still present. This study speculates that adequate vaccine protection was not achieved against the current field strain (Maradei et al., , ).…”

Section: Endemic Pools In Africamentioning

confidence: 78%

Review of the Global Distribution of Foot-and-Mouth Disease Virus from 2007 to 2014

Brito

Rodrı́guez

Hammond

et al. 2015

Transbound Emerg Dis

216

227

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Foot-and-mouth disease (FMD) virus affects livestock worldwide. There are seven different serotypes, each with a diversity of topotypes, genetic lineages and strains. Some lineages have different properties that may contribute to sporadic spread beyond their recognized endemic areas. The objective of this study was to review the most significant FMD epidemiological events that took place worldwide between 2007 and 2014. Severe epidemics were caused by FMD virus (FMDV) lineage O/Asia/Mya-98 in Japan and South Korea in 2010, both previously free of disease. In India, where FMD is endemic, the most important event was the re-emergence of lineage O/ME-SA/Ind-2001 in 2008. Notably, this lineage, normally restricted to India, Bangladesh, Nepal and Bhutan, was also found in Saudi Arabia and Libya in 2013 and has caused several outbreaks in Tunisia and Algeria in 2014-2015. In January 2011, FMDV-positive wild boars were found in Bulgaria, where the disease last occurred in 1996, followed by 12 outbreaks in livestock infected with FMDV O/ME-SA/PanAsia2. In 2012, FMDV SAT2 caused outbreaks in Egypt and the Palestinian Autonomous Territories. Another significant event was the emergence of FMDV Asia1 Sindh-08 in the Middle East. In South America, one outbreak of FMDV serotype O, topotype Euro-SA was reported in Paraguay in 2011, which was recognized as FMD-free with vaccination at the time. Lessons learned from past events, point out the need for an integrated strategy that comprises coordinated global and regional efforts for FMDV control and surveillance. Specific local characteristics related to host, environment and virus that condition FMD occurrence should be carefully considered and incorporated to adapt appropriate strategies into local plans. In this review, we compiled relevant epidemiological FMD events to provide a global overview of the current situation. We further discussed current challenges present in different FMD areas.

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Section: Endemic Pools In Africamentioning

confidence: 78%

Review of the Global Distribution of Foot-and-Mouth Disease Virus from 2007 to 2014

Brito

Rodrı́guez

Hammond

et al. 2015

Transbound Emerg Dis

216

227

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“…In addition, previous studies with FMDV serotype O indicated that cattle with serum titers !1.65 (EPP ! 75%) challenged with heterologous virus were protected [35,36]. Overall VN titers registered in this study were above this threshold.…”

Section: Discussionmentioning

confidence: 48%

“…The observation that the Korean viruses maintained reactivity with two MAbs having the capacity to in vitro neutralize the vaccine strain O 1 /Campos could account for the protective response of the O 1 /Campos against Korean isolates described in this study. Previous reports showed that animals infected with isolates lacking reactivity with these two MAbs required revaccination to attain satisfactory protection [34][35][36].…”

Section: Discussionmentioning

confidence: 99%

Efficacy of a high quality O1/Campos foot-and-mouth disease vaccine upon challenge with a heterologous Korean O Mya98 lineage virus in pigs

Novo

Malirat

Maradei

et al. 2018

Vaccine

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“…Interestingly, these strains belonging to the EURO‐SA topotype were not or barely detected even by the polyclonal antigen detection ELISA, but were recognized by another type O MAb (3C8, McCullough et al, 1987) raised against an old European type O vaccine strain. In addition, these viruses have been found to be antigenically different from other serotype O viruses from the O/EURO‐SA topotype (Maradei et al, 2011, 2014).…”

Section: Resultsmentioning

confidence: 94%

Development and validation of a simplified serotyping ELISA based on monoclonal antibodies for the diagnosis of foot‐and‐mouth disease virus serotypes O, A, C and Asia 1

Grazioli

Ferris

Dho

et al. 2020

Transbound. Emerg. Dis.

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This study describes the development and validation of a simplified enzyme-linked immunosorbent assay (ELISA) for the detection and discrimination of foot-and-mouth disease virus (FMDV) serotypes O, A, C and Asia 1. The multiplex ELISA was designed using selected, type-specific monoclonal antibodies (MAbs) coated onto ELISA plates as catching antibodies and a unique pan-FMDV MAb (1F10) as detector conjugate. Capture MAbs with the broadest intratypic reactivity were selected for each of the four FMDV serotypes by screening large panels of candidate MAbs with a wide spectrum of representative FMDV isolates. An additional pan-FMDV ELISA using 1F10 How to cite this article: Grazioli S, Ferris NP, Dho G, et al. Development and validation of a simplified serotyping ELISA based on monoclonal antibodies for the diagnosis of foot-andmouth disease virus serotypes O, A, C and Asia 1.

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Emergence of antigenic variants of Foot-and-Mouth Disease Virus serotype O in Ecuador and preliminary evaluation of a field strain as a vaccine candidate

Cited by 10 publications

References 20 publications

Review of the Global Distribution of Foot-and-Mouth Disease Virus from 2007 to 2014

Review of the Global Distribution of Foot-and-Mouth Disease Virus from 2007 to 2014

Efficacy of a high quality O1/Campos foot-and-mouth disease vaccine upon challenge with a heterologous Korean O Mya98 lineage virus in pigs

Development and validation of a simplified serotyping ELISA based on monoclonal antibodies for the diagnosis of foot‐and‐mouth disease virus serotypes O, A, C and Asia 1

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