2012
DOI: 10.1590/s1678-91992012000300009
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Abstract: Abstract:Although it is a frequent accident in a few countries, scorpion envenomation during pregnancy remains scarcely studied. In the present study, the effects of repetitive maternal exposure to Buthus occitanus tunetanus venom are investigated and its possible embryotoxic consequences on rats. Primigravid rats received a daily intraperitoneal dose of 1 mL/kg of saline solution or 300 µg/kg of crude scorpion venom, from the 7 th to the 13 th day of gestation. On the 21 st day, the animals were deeply anesth… Show more

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Cited by 4 publications
(3 citation statements)
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References 33 publications
(43 reference statements)
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“…The mechanism by which the venom increases lung weight is not clear, but the development of the lung can be altered in many ways, including the release of glucocorticoids, which presumably occurs after contact with the venom [47]. Hmed et al [48] demonstrated a similar increase after the injection of Buthus occitanus tunetanus scorpion venom, an effect related to defective placental function and to maternal hypertension and metabolic disorders.…”
Section: Discussionmentioning
confidence: 99%
“…The mechanism by which the venom increases lung weight is not clear, but the development of the lung can be altered in many ways, including the release of glucocorticoids, which presumably occurs after contact with the venom [47]. Hmed et al [48] demonstrated a similar increase after the injection of Buthus occitanus tunetanus scorpion venom, an effect related to defective placental function and to maternal hypertension and metabolic disorders.…”
Section: Discussionmentioning
confidence: 99%
“…Despite the high prevalence of scorpionism, the effect of a scorpion sting on the mother and the fetus has not been elucidated precisely. Some animal studies have been conducted to reveal these effects [27][28][29][30][31][32]. However, their results are somewhat controversial.…”
Section: Discussionmentioning
confidence: 99%
“…Similarly, the venom of the T. serrulatus provoked an increase in the weight of the lungs, liver and placenta of fetuses of mothers who received a single dose of this venom during pregnancy [37]. Ben Nars et al [49] showed a similar increase after the injection of the B. o. tunetanus venom. According to these authors, such effects are related to disabled placental function, maternal hypertension and metabolic disorders.…”
Section: Effects Of Envenomation During Pregnancy On Prenatal Developmentioning
confidence: 99%