Embryonic Toxicity of Nanoparticles

Celá, Petra; Veselá, Barbora; Matalová, Eva; Večeřa, Zbyněk; Buchtová, Marcela

doi:10.1159/000362163

Cited by 43 publications

(27 citation statements)

References 117 publications

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“…Injection of Ag NPs into chicken embryo did not result in any negative changes in SGOT or SGPT levels, in agreement with previous results from experiments carried out in ovo [38]. Some studies have reported that the size, superficial coating effect, concentration of particles, surface charge, Zeta potential, composition, and crystal form of the Ag NPs influence toxicity in embryos [39].…”

Section: Biochemical Indices (Sgot and Sgpt)supporting

confidence: 90%

Effects of in ovo Supplementation with Nano-nutrition (L-Arginine Conjugated with Ag NPs) on Muscle Growth, Immune Response and Heat Shock Proteins at Different Chicken Embryonic Development Stages

Subramaniyan¹,

Kang²,

Siddiqui³

et al. 2020

Preprint

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The aim of the study was to analyze the in ovo injection of chemically and biologically synthesized silver nano-particles (Ag NPs) using Brassica oleracea L. var capitate f. Rubra, (BOL) conjugation with L-Arginine (L-Arg) on the immune, muscle growth, survivability and hatchability of the broiler chickens. L-Arg (100 μg) conjugated with 1000 µg of Ag NPs synthesized by (BOL)-extract and L-Arg (100 μg) conjugated with 100 µg of Ag NPs chemically synthesized were injected into fertile eggs at 8d, 14d and 18d of incubation. Living embryo and hatched chicks were calculated. Survivability and hatchability were not affected by the injected dose of L-Arg (100 μg) with 1000 µg (BOL-Ag NPs) and L-Arg (100 μg) with 100 µg (C-Ag NPs) but it significantly improved when the eggs were injected on day 14 of incubation compared with those injected on days 8 or 18. Moreover, the protein expression of muscle development markers such as myogenin and myoD were significantly up-related in 14 d of incubation whereas the heat shock proteins (HSPs) such as HSP-60 and HSP-70 were significantly up-regulated in 18 d incubation. In addition, the in ovo injection on 18 d significantly increased the serum glutamate oxaloacetate transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT) as well the immunoglobulin (IgM) levels were increased in 14d incubation period in serum at the same concentration.

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Section: Biochemical Indices (Sgot and Sgpt)supporting

confidence: 90%

Effects of in ovo Supplementation with Nano-nutrition (L-Arginine Conjugated with Ag NPs) on Muscle Growth, Immune Response and Heat Shock Proteins at Different Chicken Embryonic Development Stages

Subramaniyan¹,

Kang²,

Siddiqui³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Injection of Ag NPs into chicken embryo did not result in any negative changes in SGOT or SGPT levels, in agreement with previous results from experiments carried out in ovo [8]. Some studies have reported that the size, superficial coating effect, concentration of particles, surface charge, Zeta potential, composition and crystal form of the Ag NPs influence toxicity in embryos [28]. However, the toxicity of silver nanoparticles remains controversial.…”

Section: Biochemical Indices (Sgot and Sgpt)supporting

confidence: 89%

Effects of In Ovo Supplementation with Nanonutrition (L-Arginine Conjugated with Ag NPs) on Muscle Growth, Immune Response and Heat Shock Proteins at Different Chicken Embryonic Development Stages

Subramaniyan

Kang

Siddiqui

et al. 2020

Animals

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The aim of the study was to analyze the in ovo injection of inorganic and organic synthesized silver nanoparticles (Ag NPs) using Brassica oleracea L. var. capitate F. rubra (BOL) conjugation with L-Arginine (L-Arg) on the immune, muscle growth, survivability and hatchability of broiler chickens. The conjugation of L-Arg (100 μg) with 1000 µg of Ag NPs synthesized by (BOL)-extract and L-Arg (100 μg) conjugated with 100 µg of Ag NPs inorganic synthesized were injected into fertile eggs at 8 d, 14 d and 18 d of incubation. Survival and hatching rate were significantly improved in the dose of L-Arg (100 μg) with 1000 µg (BOL-Ag NPs) and L-Arg (100 μg) with 100 µg (C-Ag NPs) on 14 d injection whereas it was decreased on 8 d or 18 d injection. Moreover, the protein expression of muscle development markers such as myogenin and myoD were significantly uprelated in 14 d of incubation whereas the heat shock proteins (HSPs), such as HSP-60 and HSP-70, were significantly upregulated in 18 d incubation. In addition, the liver function marker of serum glutamate oxaloacetate transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT) were significantly decreased and the immunoglobulin (IgM) levels were increased in a 14 d incubation period in serum at the same concentration.

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“…Tolerability and safety is discussed, e.g. in [7,[197][198][199][200][201]. It can be summarized that cosmetics and medicine might be the field of research with the greatest and most conceivable benefit of nanofluid research.…”

Section: Nanoparticles In Medicine Cosmetics and Sunscreen Productsmentioning

confidence: 99%

Nanofluids revisited

Eggers

Kabelac

2016

Applied Thermal Engineering

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h i g h l i g h t s Thermophysical properties bring nanofluids into various engineering applications. Quantity of variable parameters hinder comprehensive equations, e.g. for viscosity. Coordinated research can help to overcome debates about thermophysical properties. Missing experience for nanofluids in large scale plants. Lack of studies about high pressure/temperature applications and long term behavior. a b s t r a c tIn the roughly two decades from the first publication until today, nanofluids have found their way into various research fields. To-date published documents range from basic research to high-tech applications. This contribution aims at outlining current fields of research regarding nanofluid research. These range from fundamental property data studies presented in the first section to a listing of numerous applications of different fields of engineering. It is shown that nanofluid science pushes increasingly into the scientific world providing plenty of new questions and challenges.

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Embryonic Toxicity of Nanoparticles

Cited by 43 publications

References 117 publications

Effects of in ovo Supplementation with Nano-nutrition (L-Arginine Conjugated with Ag NPs) on Muscle Growth, Immune Response and Heat Shock Proteins at Different Chicken Embryonic Development Stages

Effects of in ovo Supplementation with Nano-nutrition (L-Arginine Conjugated with Ag NPs) on Muscle Growth, Immune Response and Heat Shock Proteins at Different Chicken Embryonic Development Stages

Effects of In Ovo Supplementation with Nanonutrition (L-Arginine Conjugated with Ag NPs) on Muscle Growth, Immune Response and Heat Shock Proteins at Different Chicken Embryonic Development Stages

Nanofluids revisited

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