Embryo Transfer: Techniques and Troubleshooting

Bhattacharyya, Jutimala; Singh, Sankalp; Das, Madhab C.; Jayaprakasan, Kanna

doi:10.1007/978-3-319-43011-9_61

Cited by 3 publications

(2 citation statements)

References 52 publications

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“…The only published RCT comparing 3D and 2D UGET showed no difference in CPR between the 2 methods 28 , yet the study did not assess the duration of procedure and did not have sufficient power to assess the differences in the subsets of women involved. Procedure associated delay may be exacerbated by additional trauma from repeated catheter adjustment required with 3D UGET 29 . Therefore, our study compared CTT with 4D UGET, a technique which removes these deficiencies identified with 3D UGET.…”

Section: Discussionmentioning

confidence: 99%

Four-dimensional ultrasound guided embryo transfers improve live birth rates when compared to the clinical touch technique: a randomised controlled trial

Nancarrow,

Tempest,

Lane

et al. 2023

Sci Rep

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Most aspects of in-vitro fertilisation (IVF) have changed dramatically since introduction, but embryo transfer (ET) technique remains largely unaltered. We aimed to determine whether four-dimensional ultrasound guided embryo transfers (4D UGET) could improve pregnancy rates when compared with clinical touch technique (CTT). This was a single centre open labelled randomised controlled trial in a tertiary fertility centre in the UK. 320 women were randomised on the day of single ET. The primary outcome was clinical pregnancy rate (CPR), secondary outcomes included live birth rate (LBR), biochemical pregnancy rate (BPR), miscarriage, pregnancy of unknown location (PUL) and ectopic pregnancy. 4D-UGET resulted in significantly higher CPR [50% vs 36% p = 0.02, OR 1.78 (1.12–2.84)] and LBR [41% vs 28%, p = 0.02, OR 1.77 (1.09–2.87)] when compared to CTT technique. Miscarriage (p = 0.49), PUL (p = 0.14) and ectopic pregnancy (p = 0.96) were similar between the two groups. LBR, from this trial, are significantly higher than the current UK average (41% vs 24%). 4D UGET allows for superior imaging of the uterine cavity, whilst tailoring the embryo deposition point specifically to the patient. Further RCTs are required to determine if these results can be replicated in other units and whether 4D UGET is superior to 2D UGET.

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Section: Discussionmentioning

confidence: 99%

Four-dimensional ultrasound guided embryo transfers improve live birth rates when compared to the clinical touch technique: a randomised controlled trial

Nancarrow,

Tempest,

Lane

et al. 2023

Sci Rep

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“…[4] Although there are many studies on this subject, most have various limitations, including low patient count, [14,15] limited age range, [16] investigation of only a few factors (loading technique, [9] endometrial thickness, [17] ABP or EFD [15,18] ), and inclusion of only particular patient groups. [6,19,20] This study aimed to investigate the effect of age and various methodological factors on pregnancy rates after ET.…”

Section: Introductionmentioning

confidence: 99%

Large-scale retrospective analysis of methodological factors affecting pregnancy rates after embryo transfer for in vitro fertilization

Kavrut,

Sagir,

Atayurt

2023

Medicine

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This study aimed to investigate the impact of methodological factors on pregnancy rates after embryo transfer (ET) for in vitro fertilization. This retrospective cross-sectional study was conducted between September 2020 and April 2022. A total of 2048 patients who underwent ultrasonography-guided first frozen embryo transfer (FET) or a fresh ET cycle due to infertility were included in the study. The effects of age, ET protocol (frozen or fresh), preimplantation genetic testing, number of embryos transferred (NET), and embryo fundus distance on pregnancy rate were investigated. The mean age of pregnant patients (31.51 ± 5.28) was significantly lower than that of non-pregnant patients (35.34 ± 6.39) (P < .001). Multiple regression analysis showed that women with lower age (P < .001), higher NET (P < .001), higher embryo fundus distance (P < .001), FET (P < .001), and preimplantation genetic testing (P = .012) had a significantly higher likelihood of pregnancy. Appropriate transfer depth, younger age, euploid embryo transfer, FET, and a higher NET can increase the likelihood of pregnancy. However, multiple factors must be considered when deciding the best protocol for a particular patient, including patient preference, costs and timing.

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Does the Time of Starting Progesterone Luteal Support Affect Embryo Transfer in Long Agonist Protocol Downregulated ICSI Cycles? A Randomized Controlled Trial

et al. 2020

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Embryo Transfer: Techniques and Troubleshooting

Cited by 3 publications

References 52 publications

Four-dimensional ultrasound guided embryo transfers improve live birth rates when compared to the clinical touch technique: a randomised controlled trial

Four-dimensional ultrasound guided embryo transfers improve live birth rates when compared to the clinical touch technique: a randomised controlled trial

Large-scale retrospective analysis of methodological factors affecting pregnancy rates after embryo transfer for in vitro fertilization

Does the Time of Starting Progesterone Luteal Support Affect Embryo Transfer in Long Agonist Protocol Downregulated ICSI Cycles? A Randomized Controlled Trial

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