Embolization complicating coronary angioplasty in the presence of an intracoronary thrombus

Weyne, Antoon E.; Heyndrickx, Guy R.; Vandekerckhove, Yves; Clément, Denis

doi:10.1002/clc.4960090915

Cited by 12 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The larger "particles" were aggregates of smaller particles that seemed to have been compressed together in the filter basket and capture sheath. The mean embolic burden per patient was 37Ϯ36 mm 2 , with a range of 0.6 to 110 mm 2 . There was a positive correlation between lesion severity and total embolic load (r 2 ϭ0.59), but it was not statistically significant.…”

Section: Morphometric and Histological Analysismentioning

confidence: 99%

“…However, the risk of distal embolization has been considered significant in the carotid arteries, in degenerated saphenous vein grafts (SVG), and in thrombotic lesions seen in the acute coronary syndrome. [1][2][3] In degenerated SVGs, the risk of distal embolization is especially high, with the "no-reflow" phenomenon being reported in up to 31.8% of cases when there is evidence of thrombus and in up to 7.9% of cases with no thrombus present. 4 This complication increases the risk of myocardial infarction and in-hospital death.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Prevention of Distal Embolization During Coronary Angioplasty in Saphenous Vein Grafts and Native Vessels Using Porous Filter Protection

et al. 2001

View full text Add to dashboard Cite

Background-Although distal embolization and the "no-reflow" phenomenon are well described in saphenous vein graft (SVG) interventions, the frequency, magnitude, and characterization of embolized debris have not been evaluated in routine coronary interventions. A unique embolus protection device described herein provides a means of containing and retrieving plaque material dislodged during percutaneous coronary interventions. This report details the first clinical experience of the effectiveness and safety of an emboli protection system in 11 SVG lesions and 15 native coronary artery lesions. Methods and Results-The AngioGuard Emboli Capture Guidewire (Cordis) consists of a PTCA wire with an expandable filter at the distal tip. The porous membrane permits normal distal blood flow, while trapping potential emboli by filtration. After crossing the lesion, the filter is expanded, and routine angioplasty is performed over the same wire. Emboli retrieval is achieved by collapsing the filter and retracting the emboli capture wire (ECW). In 26 patients, standard angioplasty was performed over the ECW; 20 of these 26 patients received a stent. Collected debris was sent for histopathological analysis. Plaque debris was retrieved after native coronary and SVG interventions in all cases. The ECW was positioned and retrieved without complications. No major adverse events occurred. Myocardial infarctions and no-reflow were not observed. Conclusions-The embolization of plaque fragments frequently occurs during coronary and SVG intervention. Distal embolization leading to microvascular obstruction and no-reflow could be successfully minimized by using the ECW.

show abstract

Section: Morphometric and Histological Analysismentioning

confidence: 99%

mentioning

confidence: 99%

Prevention of Distal Embolization During Coronary Angioplasty in Saphenous Vein Grafts and Native Vessels Using Porous Filter Protection

et al. 2001

View full text Add to dashboard Cite

show abstract

“…The risk of distal embolisation is now considered significant in carotid arteries, 2 degenerated saphenous vein graft, and in thrombotic lesions characterising the patient affected by acute coronary syndromes. [3][4][5] The process of plaque embolisation catalyses a complex interaction also involving microvascular spasm and thrombosis. This often results in diminished blood flow to the distal vascular bed, potentially complicated by periprocedural ischaemia and/or infarction or stroke.…”

mentioning

confidence: 99%