“…Because several studies have described the anti-proliferative and apoptotic-induced potential of EA that naturally occurs in plants, fruits, and vegetables, through modulation of several subcellular signaling pathways, and anti-oxidant defense mechanisms (Edderkaoui et al, 2013;Losso et al, 2004;Mishra and Vinayak, 2014a, b;Narayanan et al, 1999;Vanella et al, 2013;Zhang et al, 2014), these results are of particular relevance for the potential of the Lafoensia pacari extract itself as an anti-cancer remedy, opening the possibility that one or more compounds apart from EA in the extract are responsible for such a strong activity.…”