Elimination of Taenia solium transmission to pigs in a field trial of the TSOL18 vaccine in Cameroon

Abstract

Graphical abstract

Control of Taenia Solium Transmission of Taeniosis and Cysticercosis in Endemic Countries: The Roles of Continental Networks of Specialists and of Local Health Authorities

“…Different strategies have been proposed and tested, generally experimental and at small scale, to eradicate the (T/C) complex, the most notable being: [121], massive human cestocidal treatment associated with pig vaccination and treatment [122,123].…”

Epidemiology of Neurocysticercosis in Mexico: From a Public Health Problem to Its Control

“…The immune response was also evaluated against the vaccinating antigen by ELISA; specific, complement-fixing antibodies against the recombinant antigens increased after challenge and thereafter decreased; Furthermore, these and oncosphere antigens from other taeniid cestodes, contain a protein sequence motif suggesting a tertiary structure similar to the fibronectin type III domain [66]. Vaccination results show that pigs became protected from acquiring cysticercosis in experimental conditions, therefore they were evaluated in field trials in Peru [67] and Cameroon [68]; similar high levels of protection were obtained.…”

A Programme to Control Taeniosis-Cysticercolsis (Taenia solium) in Mexico

“…Integrated into our control programme we decided to use vaccination of pigs. Vaccines against cysticercosis, both pig, cattle and sheep have been employed in other countries and in México (Johnson et al 1989;Plancarte et al 1999;Huerta et al 2001;Flisser et al 2004;Harrison et al 2005;Gonzalez et al 2005;Assana et al 2010). The vaccine S3Pvac that we use in our control programme is produced in the Institute for Biomedical Research of UNAM.…”