Elimination of Low-Osmolality Contrast Media by Hemodialysis

Furukawa, Tomoaki; Ueda, Jun; Takahashi, S.; Sakaguchi, K.

doi:10.3109/02841859609175478

Cited by 21 publications

(20 citation statements)

References 3 publications

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“…In Cuprophan dialysers, however, a significant increase in clearance values can be obtained by an increase in the surface area. This might be the explanation for higher clearance values in the range of 110 ml/min found in previous studies with cellulose diacetate membranes and a surface area of 2.1 m 2 [5]. The comparable Cuprophan me mbrane with 1.8 m 2 in our study showed a clearance rate of 120 ml/min.…”

Section: Discussionsupporting

confidence: 44%

“…Until now there are no recommendations concerning haemodialysis after contrast medium application due to the lack of controlled studies. For most nonionic contrast media, efficient elimination rates during conventional haemodialysis with low-flux membranes have been found [3][4][5]. A comparison of the results published in the litera ture, however, shows a large variation in the haemodialy-sis procedures performed, membrane materials and surface areas used.…”

Section: Introductionmentioning

confidence: 99%

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Influence of Dialysis Procedure, Membrane Surface and Membrane Material on Iopromide Elimination in Patients with Reduced Kidney Function

Matzkies¹,

Reinecke²,

Tombach

et al. 2000

Am J Nephrol

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Haemodialysis for the elimination of contrast medium in patients with advanced renal failure is a common procedure. Even though sufficient elimination with the use of regular low-flux membranes is documented, large differences in results have been reported in prior investigations. We, therefore, compared Cuprophan and polysulfone dialysers with different surface areas to haemofiltration with different amounts of substitution fluid in 40 patients with compromised renal function after coronary angiography. Plasma iodine concentrations were measured by fluorescent excitation analysis. At constant blood flow rates of 200 ml/min, Cuprophan membranes with 1.3 m² surface area had a clearance rate of 87 ml/min, whereas polysulfone membranes of comparable size displayed a significantly higher clearance rate of 147 ml/min. Polysulfone membranes with 1.8 m² surface area showed a small but insignificant increase in the iodine clearance (162 ml/min), while Cuprophan membranes displayed an increase in clearance rates (121 ml/min). Additional ultrafiltration led to a further increase in the plasma clearance of both membranes and reduced urinary iodine excretion. Haemofiltration was comparable to haemodialysis in terms of efficacy and thus represents an alternative method. Clearance of iopromide during haemodialysis with polysulfone membranes is higher than with Cuprophan membranes. Elimination rates can be further increased by additional ultrafiltration. Haemofiltration is comparable to haemodialysis regarding contrast medium elimination.

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Section: Discussionsupporting

confidence: 44%

Section: Introductionmentioning

confidence: 99%

Influence of Dialysis Procedure, Membrane Surface and Membrane Material on Iopromide Elimination in Patients with Reduced Kidney Function

Matzkies¹,

Reinecke²,

Tombach

et al. 2000

Am J Nephrol

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“…For iohexol, values of 81 to 138 d m i n have been reported (5,8,14), and for iopromide 80 d m i n (7). The ioversol dialysance in our study is similar to that of other nonionic monomeric CM.…”

Section: Discussionmentioning

confidence: 99%

Elimination of Ioversol by Hemodialysis

Ueda¹,

Furukawa²,

Takahashi³

et al. 1996

Acta Radiol

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“…Hemodialysis effectively removes radiocontrast [126][127][128] and has been proposed as a prophylaxis treatment for contrast-induced nephropathy. Four small randomized trials have considered this question in patients with impaired renal function.…”

Section: Extracorporeal Removal Of Contrastmentioning

confidence: 99%

Prophylaxis Strategies for Contrast-Induced Nephropathy

Pannu

Wiebe²,

Tonelli³

2006

JAMA

353

200

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While several risk factors for contrast-induced nephropathy have been identified, the development of an effective prophylaxis strategy for contrast-induced nephropathy has been limited by our poor understanding of the pathophysiology and the clinical significance of this condition. Future research should focus on correctly identifying higher-risk patients and testing therapies in the setting of large well-powered clinical trials.

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Elimination of Low-Osmolality Contrast Media by Hemodialysis

Cited by 21 publications

References 3 publications

Influence of Dialysis Procedure, Membrane Surface and Membrane Material on Iopromide Elimination in Patients with Reduced Kidney Function

Influence of Dialysis Procedure, Membrane Surface and Membrane Material on Iopromide Elimination in Patients with Reduced Kidney Function

Elimination of Ioversol by Hemodialysis

Prophylaxis Strategies for Contrast-Induced Nephropathy

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