ELF18‐INDUCED LONG NONCODING RNA 1 evicts fibrillarin from mediator subunit to enhance <i>PATHOGENESIS‐RELATED GENE 1</i> (<i>PR1</i>) expression

Seo, Jun Sung; Diloknawarit, Piyarut; Park, Bong Soo; Chua, Nam‐Hai

doi:10.1111/nph.15530

Cited by 90 publications

(65 citation statements)

References 54 publications

(79 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More recently, analysis of fib2 knockout plants demonstrated that FIB2 binds to and negatively regulates the expression of innate immune response genes in Arabidopsis. Upon Pseudomonas syringae inoculation, FIB2 interacts with ELF18-INDUCED LONG-NONCODING RNA1 (ELENA1) and is then evicted from gene promoters to activate innate immune response genes (Seo et al, 2018). Taken together, these findings suggest that FIB1 and FIB2 play distinct roles in the modification of and interaction with RNA, DNA, and/ or histone proteins in Arabidopsis.…”

Section: Rrna Processing Factorsmentioning

confidence: 97%

Ribosome Biogenesis in Plants: From Functional 45S Ribosomal DNA Organization to Ribosome Assembly Factors

2019

View full text Add to dashboard Cite

The transcription of 18S, 5.8S, and 18S rRNA genes (45S rDNA), cotranscriptional processing of pre-rRNA, and assembly of mature rRNA with ribosomal proteins are the linchpins of ribosome biogenesis. In yeast (Saccharomyces cerevisiae) and animal cells, hundreds of pre-rRNA processing factors have been identified and their involvement in ribosome assembly determined. These studies, together with structural analyses, have yielded comprehensive models of the pre-40S and pre-60S ribosome subunits as well as the largest cotranscriptionally assembled preribosome particle: the 90S/small subunit processome. Here, we present the current knowledge of the functional organization of 45S rDNA, pre-rRNA transcription, rRNA processing activities, and ribosome assembly factors in plants, focusing on data from Arabidopsis (Arabidopsis thaliana). Based on yeast and mammalian cell studies, we describe the ribonucleoprotein complexes and RNA-associated activities and discuss how they might specifically affect the production of 40S and 60S subunits. Finally, we review recent findings concerning pre-rRNA processing pathways and a novel mechanism involved in a ribosome stress response in plants

show abstract

Section: Rrna Processing Factorsmentioning

confidence: 97%

Ribosome Biogenesis in Plants: From Functional 45S Ribosomal DNA Organization to Ribosome Assembly Factors

2019

View full text Add to dashboard Cite

show abstract

“…Thus, here we describe a previously unappreciated function for plant CBs and the nucleolus in plant defence responses. Interestingly, another nucleolar (also found in CBs) protein, fibrillarin 2 also has been assumed to play an important role in plant defence by interacting with the RNA polymerase II transcription Mediator complex MED19a subunit controlling expression of PR-1 genes (B€ ackstr€ om et al, 2007;Seo et al, 2018;Soutourina, 2018).…”

Section: Researchmentioning

confidence: 99%

Interaction of a plant virus protein with the signature Cajal body protein coilin facilitates salicylic acid‐mediated plant defence responses

et al. 2019

View full text Add to dashboard Cite

Summary In addition to well‐known roles in RNA metabolism, the nucleolus and Cajal bodies (CBs), both located within the nucleus, are involved in plant responses to biotic and abiotic stress. Previously we showed that plants in which expression of the CB protein coilin is downregulated are more susceptible to certain viruses including tobacco rattle virus (TRV), suggesting a role of coilin in antiviral defence. Experiments with coilin‐deficient plants and the deletion mutant of the TRV 16K protein showed that both 16K and coilin are required for restriction of systemic TRV infection. The potential mechanisms of coilin‐mediated antiviral defence were elucidated via experiments involving co‐immunoprecipitation, use of NahG transgenic plants deficient in salicylic acid (SA) accumulation, measurement of endogenous SA concentrations and assessment of SA‐responsive gene expression. Here we show that TRV 16K interacts with and relocalizes coilin to the nucleolus. In wild‐type plants these events are accompanied by activation of SA‐responsive gene expression and restriction of TRV systemic infection. By contrast, viral systemic spread was enhanced in NahG plants, implicating SA in these processes. Our findings suggest that coilin is involved in plant defence, responding to TRV infection by recognition of the TRV‐encoded 16K protein and activating SA‐dependent defence pathways.

show abstract

“…Moreover, LncRNA39026 enhances tomato resistance to P. infestans by decoying miR168a and inducing PR genes' expression [71]. lncRNA directly binds to protein mediator as a molecular decoy of FIBRILLARIN 2 (FIB2) to regulate gene transcription of ELF18-induced long noncoding RNA1 (ELENA1) regulating PR1 in Arabidopsis [72]. After Bgt and Pst infection in wheat, 101 lncRNAs were predicted to be the target of miRNA using psRNATarget, including miR156, miR160, miR164, miR167, miR393, miR398, miR829, and so on.…”

Section: Regulation Of Defense Against Fungal Stress As Molecular Spomentioning

confidence: 99%

“…The ELF18-INDUCED LONG-NONCODING RNA1 (ELENA1), as a factor enhancing resistance against Pseudomonas syringe pv. tomato DC3000, directly interacts with FIB2 and mediator subunit 19a (FIB2/MED19a) and affects the enrichment of MED19a on the PR1 promoter [41,72]. Overexpressing lncRNA LAIR was proven to increase grain yield and regulate the neighboring gene cluster's expression in rice [14].…”

Section: Prospect Of Plant Lncrnas Related To Resistancementioning

confidence: 99%

The Emerging Role of Long Non-Coding RNAs in Plant Defense Against Fungal Stress

Zhang

Guo

et al. 2020

IJMS

View full text Add to dashboard Cite

Growing interest and recent evidence have identified long non-coding RNA (lncRNA) as the potential regulatory elements for eukaryotes. LncRNAs can activate various transcriptional and post-transcriptional events that impact cellular functions though multiple regulatory functions. Recently, a large number of lncRNAs have also been identified in higher plants, and an understanding of their functional role in plant resistance to infection is just emerging. Here, we focus on their identification in crop plant, and discuss their potential regulatory functions and lncRNA-miRNA-mRNA network in plant pathogen stress responses, referring to possible examples in a model plant. The knowledge gained from a deeper understanding of this colossal special group of plant lncRNAs will help in the biotechnological improvement of crops.

show abstract

ELF18‐INDUCED LONG NONCODING RNA 1 evicts fibrillarin from mediator subunit to enhance PATHOGENESIS‐RELATED GENE 1 (PR1) expression

Cited by 90 publications

References 54 publications

Ribosome Biogenesis in Plants: From Functional 45S Ribosomal DNA Organization to Ribosome Assembly Factors

Ribosome Biogenesis in Plants: From Functional 45S Ribosomal DNA Organization to Ribosome Assembly Factors

Interaction of a plant virus protein with the signature Cajal body protein coilin facilitates salicylic acid‐mediated plant defence responses

The Emerging Role of Long Non-Coding RNAs in Plant Defense Against Fungal Stress

Contact Info

Product

Resources

About