Elevated serum amylase in patients with chronic pancreatitis: Acute attack or macroamylasemia?

Губергріц, Н. Б.; Golubova, Oksana; Лукашевич, Г. М.; Фоменко, П. Г.

doi:10.1016/j.pan.2013.12.004

Cited by 9 publications

(8 citation statements)

References 12 publications

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“…Clinically, the variation of serum amylase is closely related to pancreatic disease such as pancreatitis, pancreatic exocrine dysfunction and pancreatic tumor. [22][23][24] The present evidence suggests a significant link between serum amylase activity and ABO blood type in Chinese subjects, the important implication of our findings is that ABO blood type may be associated with the susceptibility of pancreatic disease.…”

Section: Discussionsupporting

confidence: 60%

“…Additional study is needed to confirm the current results, in the current study, healthy individuals with O blood type maintain elevated serum amylase activity, and the fascinating relationship should be born and natural. Clinically, the variation of serum amylase is closely related to pancreatic disease such as pancreatitis, pancreatic exocrine dysfunction and pancreatic tumor . The present evidence suggests a significant link between serum amylase activity and ABO blood type in Chinese subjects, the important implication of our findings is that ABO blood type may be associated with the susceptibility of pancreatic disease.…”

Section: Discussionsupporting

confidence: 60%

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Serum amylase activity altered by the ABO blood group system in Chinese subjects

Peng

Goyal

Lin

et al. 2019

Clinical Laboratory Analysis

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ObjectiveThe underlying interactions between ABO blood group antigens and pancreatic exocrine tissue have been demonstrated, and serum amylase was synthesized by pancreatic ductal cells. Thus, we investigated the link between ABO blood type and serum amylase activity in Chinese subjects.MethodsOur study included 343 relatively healthy Chinese individuals, and the data were retrieved from electronic medical record database.ResultsA increased trend was observed for serum amylase activity in ABO blood type distribution, and we found that serum amylase activity was remarkable increased in subjects with O blood type compared to those with non‐O blood type (P = 0.013). Logistic regression analysis indicated that serum amylase was independently associated with individuals with O blood group (adjusted odds ratio 1.574; 95% CI, 1.022‐2.425, P = 0.039).ConclusionsThe present evidence suggests a significant link between serum amylase activity and ABO blood type in the study population, indicating ABO blood type may be associated with the susceptibility of pancreatic disease.

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Section: Discussionsupporting

confidence: 60%

Section: Discussionsupporting

confidence: 60%

Serum amylase activity altered by the ABO blood group system in Chinese subjects

Peng

Goyal

Lin

et al. 2019

Clinical Laboratory Analysis

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“…Except hydroxyproline, the combinations of tested serum amylase and lipase also provide diagnostic information for CP [33]. In this study, serum AMS and lipase are taken as pivotal biochemical indices for assessing the success of CP modeling and the curative effect of GLPS 3 .…”

Section: Discussionmentioning

confidence: 99%

Effects of Ganoderma lucidum polysaccharides on chronic pancreatitis and intestinal microbiota in mice

Zhuo

Teng

et al. 2016

International Journal of Biological Macromolecules

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“…In serum, elevated levels of amylase are strongly associated with inflammation, and levels of the enzyme are used as an indicator of pancreatitis [79]. Annexin A1 plays an important part in the innate immune response as it affects glucocorticoid-mediated responses and thus regulates inflammatory process.…”

Section: (I) Dmbt-1 and Transglutaminasementioning

confidence: 99%

Identification of proteins from 4200-year-old skin and muscle tissue biopsies from ancient Egyptian mummies of the first intermediate period shows evidence of acute inflammation and severe immune response

Jones

Mirzaei

Ravishankar

et al. 2016

Phil. Trans. R. Soc. A.

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We performed proteomics analysis on four skin and one muscle tissue samples taken from three ancient Egyptian mummies of the first intermediate period, approximately 4200 years old. The mummies were first dated by radiocarbon dating of the accompany-\break ing textiles, and morphologically examined by scanning electron microscopy of additional skin samples. Proteins were extracted, separated on SDS–PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis) gels, and in-gel digested with trypsin. The resulting peptides were analysed using nanoflow high-performance liquid chromatography–mass spectrometry. We identified a total of 230 unique proteins from the five samples, which consisted of 132 unique protein identifications. We found a large number of collagens, which was confirmed by our microscopy data, and is in agreement with previous studies showing that collagens are very long-lived. As expected, we also found a large number of keratins. We identified numerous proteins that provide evidence of activation of the innate immunity system in two of the mummies, one of which also contained proteins indicating severe tissue inflammation, possibly indicative of an infection that we can speculate may have been related to the cause of death. This article is part of the themed issue ‘Quantitative mass spectrometry’.

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Elevated serum amylase in patients with chronic pancreatitis: Acute attack or macroamylasemia?

Cited by 9 publications

References 12 publications

Serum amylase activity altered by the ABO blood group system in Chinese subjects

Serum amylase activity altered by the ABO blood group system in Chinese subjects

Effects of Ganoderma lucidum polysaccharides on chronic pancreatitis and intestinal microbiota in mice

Identification of proteins from 4200-year-old skin and muscle tissue biopsies from ancient Egyptian mummies of the first intermediate period shows evidence of acute inflammation and severe immune response

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