Elevated Red Blood Cell Distribution width in Healthy Smokers

Kurtoğlu, Ertuğrul; Aktürk, Erdal; Korkmaz, Hasan; Sıncer, İsa; Yılmaz, Mücahid; Erdem, Kenan; Çelik, Ahmet; Оздемир, Рамазан

doi:10.1016/j.jacc.2013.08.373

Cited by 18 publications

(22 citation statements)

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“…Although no statistically significant correlation is seen between smoking and RDW, a significant increase in RDW of smokers (15.42±1.22 %) is seen as compared to non-smokers (14.85±0.82 %). A similar result has been put forth by Kurtoğlu et al, (2013) [16].…”

Section: Discussionsupporting

confidence: 85%

Comparison of Taste Threshold in Smokers and Non-Smokers Using Electrogustometry and Fungiform Papillae Count: A Case Control Study

Khan

Narayanan

Puttabuddi

et al. 2016

JCDR

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Section: Discussionsupporting

confidence: 85%

Comparison of Taste Threshold in Smokers and Non-Smokers Using Electrogustometry and Fungiform Papillae Count: A Case Control Study

Khan

Narayanan

Puttabuddi

et al. 2016

JCDR

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“…In a study conducted in our country the mean RDW values were found higher in smokers than in nonsmokers, and also significant positive correlations between RDW and number of cigarettes smoked per day and between RDW and duration of smoking were identified. They concluded that elevated RDW is associated with cigarette smoking and may be a useful indicator of inflammatory activity in smokers (15). In accordance with the current literature, RDW was observed in association with smoking in our study results also.…”

Section: Discussionsupporting

confidence: 93%

Do we care enough about the role of smoking in the etiology of polycythemia?

Öcal¹,

Arslan²,

Ozgur³

et al. 2019

Gulhane Med J

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In this study, we aimed to determine the hematopoietic effects of tobacco use and amount of usage, and to determine its possible relationships with secondary polycythemia in patients without active pulmonary pathology. Methods Patients who were diagnosed with polycythemia in the Hematology Department and referred to the Chest Diseases Department for the purpose of investigating possible secondary polycythemia etiologies during the last one year were reviewed retrospectively. The ethical approval number is 18/182. Data

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“…The literature typically shows higher levels in smokers versus non‐smokers on these parameters . The mechanism of hematological changes associated with smoking is not wholly understood, and can be a combination of multiple factors.…”

Section: Discussionmentioning

confidence: 99%

“…The findings of the other studied biomarkers were either inconclusive or showed no difference based on the Bayes factors analysis. The literature typically shows higher levels in smokers versus non-smokers on these parameters [13,[35][36][37][38][39]. The mechanism of hematological changes associated with smoking is not wholly understood, and can be a combination of multiple factors.…”

Section: Discussionmentioning

confidence: 99%

Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects

et al. 2019

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Aim A previous study showed significantly greater reductions in number of cigarettes smoked and biomarkers of toxicant and carcinogen exposure in smokers assigned to immediate reduction of nicotine in cigarettes to very low levels versus gradually over time or continued smoking of normal nicotine content cigarettes. This study examines the effects of these approaches on selected biomarkers associated with harmful biological effects. Design Three‐arm, randomized controlled trial. Setting Ten United States academic institutional sites. Participants Daily smokers uninterested in quitting smoking with a mean age of 45.1 [standard deviation (SD) = 13.4)] years and smoking 17.1 (SD = 8.5) cigarettes/day; 43.9% (549 of 1250) female; 60.6% (758 of 1250) white ethnicity. Interventions (1) Smoking cigarettes where nicotine content was immediately reduced to very low levels (n = 503); (2) smoking cigarettes where nicotine content was gradually reduced, with dose changes occurring monthly (n = 498); and (3) continued smoking with normal nicotine content cigarettes (n = 249). Measurements Smokers were assessed at baseline while smoking their usual brand cigarettes, and again at 4, 8, 12, 16 and 20 weeks. Outcomes were areas under the concentration time curve (AUC) for the period of study of biomarkers of inflammation, oxidative stress and hematological parameters. Findings No consistent significant differences were observed across groups (Bayes factors showing data to be insensitive), with the only exception being red blood cell size variability, which was observed to be lower in the immediate versus gradual nicotine reduction [mean difference = −0.11; 95% confidence interval (CI) = –0.18, −0.04, P = 0.004] and normal nicotine control groups (mean difference = − 0.15, 95% CI = –0.23, −0.06, P = 0.001). Conclusion It remains unclear whether switching to very low nicotine cigarettes leads to a short‐term reduction in biomarkers of tobacco‐related harm.

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Elevated Red Blood Cell Distribution width in Healthy Smokers

Cited by 18 publications

References 0 publications

Comparison of Taste Threshold in Smokers and Non-Smokers Using Electrogustometry and Fungiform Papillae Count: A Case Control Study

Comparison of Taste Threshold in Smokers and Non-Smokers Using Electrogustometry and Fungiform Papillae Count: A Case Control Study

Do we care enough about the role of smoking in the etiology of polycythemia?

Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects

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