Elevated rates and altered characteristics of the clearance of carbon from the blood of rabbits with variations in environmental conditions

The mechanism of enhanced clearance of colloidal carbon from the blood of rabbits stimulated with a tubercle bacillary lipid

“…after injection of the carbon occurs, after which the rate slows down. Thus the logarithmic plot of concentration of carbon in the blood against time after injection of the carbon becomes biphasic and not a single straight line Donald, 1972). The hypothesis was put forward that separate functions are affected at different times after the injection of lipid and that these relate to individual cell function at the early stage and to cell numbers at later times.…”

“…A control animal was always tested at the same time as each lipid-treated animal. These precautions were necessary to ensure that carbon clearance was not augmented as a result of environmental factors (Donald, 1972).…”

An electron‐microscope study of defibrination during carbon clearance in rabbits stimulated by a tubercle bacillary lipid

“…Thus, functional changes in carbon clearance rates, similar in character to those produced by this lipid, have been shown in some conditions of environmental stress on the animals (Donald, 1972a). Also, the enhanced clearance of colloidal carbon after the injection of endotoxin (Biozzi, Benacerraf and HaIpern, 1955), zymosan (Cutler, 1960) and complete Freund's adjuvant (Nicol, Quantock and Vernon-Roberts, 1966) may be associated with similar phenomena.…”

The effect of Mycoplasma arthritidis infection on the phagocytic activity of macrophages in rats and mice

“…Standard food and water were supplied. These conditions were necessary to avoid possible environmental effects on the clearance rate of colloidal carbon [9].…”