Elevated Parathyroid Hormone-Related Protein and Hypercalcemia in a Patient With Cutaneous Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa

Welsh, David A.; Powers, Jacqueline

doi:10.1097/00007611-199312000-00018

Cited by 21 publications

(14 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This complication is uncommon: since 1958 only 52 cases have been published, most often as case reports – 27 cases were reported in a review in 1995 [15], which omitted 3 additional ones reported up to that time period [16,17,18], 22 additional cases were then published from 1995 to 2008 [19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36]. Lapins et al [37] reported 5 cases of ‘nonmelanoma skin cancer’ among a cohort that may contain some patients who did not have criteria for HS so we did not include those results.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological Study of 13 Cases of Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa

et al. 2009

View full text Add to dashboard Cite

Background: To the best of our knowledge, only 52 cases of squamous cell carcinoma (SCC) complicating hidradenitis suppurativa (HS) have been reported since 1958. We describe 13 new cases. Methods: We propose a clinical and histological analysis of our cases. We include these results in a review of previously reported cases to analyze a total of 65 patients. In our series of 13 cases, we also investigate the presence of human papillomavirus (HPV) in tumor samples, by polymerase chain reaction (PCR) on paraffin-embedded material. Results: Malignant transformation affects mainly men with a long-term history of genitoanal HS. Although our cases were 7 well-differentiated carcinomas and 6 verrucous carcinomas, lymphatic and visceral metastasis occurred in 2 and 3 cases, respectively. With PCR, we demonstrated presence of HPV in genitoanal tumoral lesions, principally HPV-16. Conclusion: SCC complicating HS evolves poorly, despite a good histological prognosis. Our results sustain the implication of HPV in the malignant transformation of HS.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinicopathological Study of 13 Cases of Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa

et al. 2009

View full text Add to dashboard Cite

show abstract

“…88,111 Squamous cell carcinomas originating from HS lesions may be associated with hypercalcemia. 112 A general association between HS and cancer was confirmed in a nationwide case-control study involving all Swedish HS patients admitted to hospital between 1987 and 94. 96 It was shown that HS patients have a higher overall incidence of cancer (1.5; 1.1-1.8) than the general population.…”

Section: Consequences and Complicationsmentioning

confidence: 90%

Hidradenitis Suppurativa

Jemec

2002

JCMS

View full text Add to dashboard Cite

show abstract

“…Environ 50 cas sont rapportés dans la littérature [1][2][3][4][5]. Environ 50 cas sont rapportés dans la littérature [1][2][3][4][5].…”

Section: Discussionunclassified

Hypercalcémie aiguë et carcinomes épidermoïdes multiples compliquant une hidradénite suppurée

et al. 2009

View full text Add to dashboard Cite

Elevated Parathyroid Hormone-Related Protein and Hypercalcemia in a Patient With Cutaneous Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa

Cited by 21 publications

References 0 publications

Clinicopathological Study of 13 Cases of Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa

Clinicopathological Study of 13 Cases of Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa

Hidradenitis Suppurativa

Hypercalcémie aiguë et carcinomes épidermoïdes multiples compliquant une hidradénite suppurée

Contact Info

Product

Resources

About