Abstract:Increased NLR may be useful as an indicator of the presence of HT, especially in complicated cases. NLR is inexpensive and easy to determine. Larger, prospective studies are required to determine its usefulness in assessing diagnostic potential and treatment outcomes in HT patients.
“…In another study, it has been suggested that NLR may be more valuable than other markers in anticipating bacteremia under emergency conditions. NLR has been also shown to be present as a marker in infl ammatory diseases (17). In our study, we have reached the conclusion that NLR can be used as an indicator of infl ammation by reasoning that NLR was higher in the infected group compared to the non-infected group.…”
AIM: To investigate the relationship between hemogram parameters and bacterial growth in cultures of blood, urine or sputum in intensive care unit patients. METHODS: This retrospective, observational, cross-sectional study was conducted in a tertiary referral hospital between March 2015 and December 2017. Baseline demographic and clinical characteristics, hemogram parameters and other laboratory test results of patients admitted to intensive care unit were recorded. Patients were divided into two groups as patients who were infected, and those who did not have any infectious agents grown in the culture dish, and then the groups were compared with each other. RESULTS: There were no signifi cant differences between the groups in terms of baseline demographic and clinical characteristics. When the groups were compared in terms of hemogram parameters, the neutrophil-to-lymphocyte ratio (p < 0.001), platelet-to-lymphocyte ratio (p = 0.013), plateletcrit (p = 0.028) and mean platelet volume (p < 0.001) were signifi cantly higher in infected patients than in non-infected patients. CONCLUSION: We suggest that neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, plateletcrit, and mean platelet volume could be used as infection markers in the intensive care unit population (Tab. 1, Ref. 25).
“…In another study, it has been suggested that NLR may be more valuable than other markers in anticipating bacteremia under emergency conditions. NLR has been also shown to be present as a marker in infl ammatory diseases (17). In our study, we have reached the conclusion that NLR can be used as an indicator of infl ammation by reasoning that NLR was higher in the infected group compared to the non-infected group.…”
AIM: To investigate the relationship between hemogram parameters and bacterial growth in cultures of blood, urine or sputum in intensive care unit patients. METHODS: This retrospective, observational, cross-sectional study was conducted in a tertiary referral hospital between March 2015 and December 2017. Baseline demographic and clinical characteristics, hemogram parameters and other laboratory test results of patients admitted to intensive care unit were recorded. Patients were divided into two groups as patients who were infected, and those who did not have any infectious agents grown in the culture dish, and then the groups were compared with each other. RESULTS: There were no signifi cant differences between the groups in terms of baseline demographic and clinical characteristics. When the groups were compared in terms of hemogram parameters, the neutrophil-to-lymphocyte ratio (p < 0.001), platelet-to-lymphocyte ratio (p = 0.013), plateletcrit (p = 0.028) and mean platelet volume (p < 0.001) were signifi cantly higher in infected patients than in non-infected patients. CONCLUSION: We suggest that neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, plateletcrit, and mean platelet volume could be used as infection markers in the intensive care unit population (Tab. 1, Ref. 25).
“…Whereas, in a study by Cıray et al there was no difference among NLR between the patients with or without diabetic retinopathy (23). Also there are studies in which Hashimoto thyroiditis, which is one of the autoimmune thyroid diseases, is found to be signifi cantly higher than in the NLR and PLR control group (24) and before treatment than after levothroxine replacement (22). Despite the development of a similar autoimmune process with Graves' disease in Hashimoto thyroiditis, the thyroid hormone levels and the used medication are different.…”
AIM: While the ratio of neutrophil-to-lymphocyte (NLR) increases with infl ammation, its importance in Graves' disease is not clear. The aim of this study was to evaluate NLR, a marker of chronic infl ammmation, in Graves' disease. METHODS: 86 Graves' patients (37 before treatment,49 euthyroid patients after treatment) and 112 controls were enrolled. Hematologic parameters, thyroid function tests, age and gender were recorded. NLRs were calculated. Firstly, groups were composed as Graves' group (Group1) and participants without thyroid disorder as control group (Group2). Secondly, Graves' patients before treatment were considered as Group1a, euthyroid Graves' patients after antithyroid treatment were considered as Group1b. These groups were compared with each other in terms of descriptive data and hematological parameters. RESULTS: Lymphocyte, monocyte, platelet, free T3, and free T4 levels were signifi cantly higher in Graves' group than the controls. TSH and NLR were signifi cantly lower in Graves' group Graves' than the controls. Differences among group1a and group1b for monocyte (p = 0.013), for basophil (p= 0.002), for platelet (p = 0.029), and for NLR (p = 0.029) were statistically signifi cant. CONCLUSION: Unlike other infl ammatory diseases, in Graves' disease; hematological parameters may not give information about infl ammatory state of the disease. Therefore, NLR should be evaluated with other serum infl ammatory markers in Graves' disease (Tab. 2, Fig. 1, Ref. 26).
“…It is known that white blood cells differ in systemic inflammation, such as neutrophilia and lymphopenia. 6 This inflammatory response and tissue necrosis leads to fibrosis and poor recipient vascularity, which likely has a key role in deficient wound healing, which, in turn, threatens urethroplasty success. 22 In a related study of 208 patients with a history of urethral stricture after transurethral resection of the prostate, it was shown that the NLR was relatively higher in relapsed patients but not significant.…”
SUMMARY INTRODUCTION Due to spongiofibrosis and inflammatory processes underlying the pathogenesis of urethral stricture, it is possible that the neutrophil-lymphocyte ratio (NLR) may give essential information about the course of the disease and recurrence possibilities. Our study aims to evaluate the correlation between NLR and recurrence rates. METHODS A total of 512 patients who underwent direct visual internal urethrotomy (DVIU) due to urethral stricture in our clinic between February 2010 and January 2018 were evaluated retrospectively. RESULTS The median follow up for non-recurrent and recurrent groups after DVIU was 30 and 36 months, respectively. During the follow-up, 280 (54.7%) of the patients had recurrences, and 232 (45,3%) had no recurrences. The mean time for recurrence after DVIU was 6,5±1,4 months, with a range of 1-36 months. The mean NLR in the non-recurrence group was 2,02±0,87, with a median of 1.9, and 3,66±2,30, with a median of 3 in the recurrence group. A highly significant statistical difference was observed between two groups in terms of neutrophil count and NLR (p: 0.000 – both). The area under curve value for NLR was 0.767, with a standard error of 0.021 (95% CI 0.727-0.808). The cut-off value of NLR was determined as 2.25, with a 70% sensitivity and 67,7% specificity. CONCLUSION By using NLR, the inflammatory features of the urethral tissue can be predicted, and possible recurrences after surgery can be estimated. Consequently, open urethroplasty techniques can be used in cases with a significant NLR value instead of the recurrent endoscopic procedure.
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