Elevated 18F-fluorodeoxyglucose uptake in the interventricular septum is associated with atrioventricular block in patients with suspected cardiac involvement sarcoidosis

Manabe, Osamu; Ohira, Hiroshi; Yoshinaga, Keiichiro; Sato, Takahiro; Klaipetch, Alisa; Oyama‐Manabe, Noriko; Ito, Yoichi M.; Tsujino, Ichizo; Nishimura, Masaharu; Tamaki, Nagara

doi:10.1007/s00259-013-2460-5

Cited by 45 publications

(25 citation statements)

References 38 publications

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“…3 The key to an effective preparation protocol is finding a method to optimally suppress physiological myocardial 18 FDG uptake in order to allow 18 FDG detection in pathological myocardium. 4 …”

Section: Introductionmentioning

confidence: 99%

Opening the door to noninvasive assessment of cardiac transplant rejection: It’s all in the preparation

Jayadeva

Better

2020

Journal of Nuclear Cardiology

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Section: Introductionmentioning

confidence: 99%

Opening the door to noninvasive assessment of cardiac transplant rejection: It’s all in the preparation

Jayadeva

Better

2020

Journal of Nuclear Cardiology

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“…The most common site is the left ventricular free wall followed by the intraventricular septum (21). In cases of conduction abnormality, it is quite important to look at the intraventricular septum (22).…”

Section: F-fdg Image Interpretationmentioning

confidence: 99%

Japanese Guidelines for Cardiac Sarcoidosis

Yoshinaga

Miyagawa

Kiso

et al. 2017

Annals of Nuclear Cardiology

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For patients with sarcoidosis involving organs, those with cardiac lesions have especially poor prognosis. Among sarcoidosis patients, those in Japan have higher rates of cardiac involvement of sarcoidosis (CS) than do those in other countries. Therefore, the Japanese medical community has put great efforts into managing CS patients and has developed research activities. In this regard, the Japanese Ministry of Health & Welfare (JMHW) issued CS diagnostic guidelines in 1993 and these have been widely used around the world. The Japanese Circulation Society updated its nuclear medicine guidelines in 2010 and recommended using nuclear imaging to diagnose CS.

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“…74 Moreover, 18F-FDG uptake is predictive of adverse outcomes in sarcoidosis, such as cardiac death, conduction block and ventricular arrhythmia. 75,76 Acute Transplant Rejection Noninvasive imaging can be useful for monitoring the cellular infiltration that occurs in case of acute cardiac transplant rejection. Because the sensitivity of current T2 WI and LGE is insufficient for detecting acute cellular rejection, several MRI tracers have been tested, mostly in animal models.…”

Section: Myocarditis and Cardiac Sarcoidosismentioning

confidence: 99%

Magnetic Resonance Imaging and Positron Emission Tomography Approaches to Imaging Vascular and Cardiac Inflammation

Amsallem

Saito

Tada

et al. 2016

Circ J

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Inflammation plays a significant role in a wide range of cardiovascular diseases (CVDs). The numerous implications of inflammation in all steps of CVDs, including initiation, progression and complications, have prompted the emergence of noninvasive imaging modalities as diagnostic, prognostic and monitoring tools. In this review, we first synthesize the existing evidence on the role of inflammation in vascular and cardiac diseases, in order to identify the main targets used in noninvasive imaging. We chose to focus on positron emission tomographic (PET) and magnetic resonance imaging (MRI) studies, which offer the greatest potential of translation and clinical application. We detail the main preclinical and clinical studies in the following CVDs: coronary and vascular atherosclerosis, abdominal aortic aneurysms, myocardial infarction, myocarditis, and acute heart transplant rejection. We highlight the potential complementary roles of these imaging modalities, which are currently being studied in the emerging technology of PET/MRI. Finally, we provide a perspective on innovations and future applications of noninvasive imaging of cardiovascular inflammation. (Circ J 2016; 80: 1269 -1277

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Elevated 18F-fluorodeoxyglucose uptake in the interventricular septum is associated with atrioventricular block in patients with suspected cardiac involvement sarcoidosis

Cited by 45 publications

References 38 publications

Opening the door to noninvasive assessment of cardiac transplant rejection: It’s all in the preparation

Opening the door to noninvasive assessment of cardiac transplant rejection: It’s all in the preparation

Japanese Guidelines for Cardiac Sarcoidosis

Magnetic Resonance Imaging and Positron Emission Tomography Approaches to Imaging Vascular and Cardiac Inflammation

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