Electrosurgical Loop Excision of the Cervix

Newkirk, Gary R.

doi:10.1016/s0095-4543(05)70394-8

Cited by 6 publications

(2 citation statements)

References 16 publications

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“…Minor complications leading to patients returning to the clinic for evaluation occurred in less than 15% of women, and major short-term complications requiring hospitalization, surgery, or both occurred in no more than 2.0% of women [56,59,60]. Asymptomatic cervical stenosis (i.e., a stenosis revealed only by the inability to pass a fine probe through the cervical canal) was observed in up to 4%-6% of women [60,61]. Our findings appear to be of the same order of magnitude, although few of the studies included in our review reported on the frequency of complications leading to outpatient visit or hospitalization.…”

Section: Discussionmentioning

confidence: 99%

Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scaling-up of cervical screening programs? A systematic review

et al. 2010

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BackgroundSince the mid-1990s, there have been growing efforts to prevent cervical cancer in less-developed countries through the development of innovative screening approaches such as visual inspection of the cervix associated with same day management of cervical lesions with cryotherapy or loop electrosurgical excision procedure (LEEP). In the past, promising cancer screening interventions have been widely promoted despite incomplete evidence, only to become the subject of intense controversies about ensuing net health benefit. Because the efficacy and effectiveness of the new protocols for global cervical cancer screening have not been well characterized yet, and as a contribution to the evaluation of the balance between the benefits and risks of these protocols, we reviewed the literature on the safety of cryotherapy and LEEP for cervical intraepithelial neoplasia (CIN) in low- and middle-income countries.MethodsWe searched 12 databases (Medline, Google Scholar, Scopus, Cochrane Library, Web of Science, OCLC, PAIS International Database, WHO Global Health Library, CINAHL, Science.gov, NYAM Grey Literature Report, and POPLINE) for original research published between January 1995 and April 2009. Both peer-reviewed publications and items of "grey" literature were retrieved; no language restriction was applied. We calculated the median (minimum, maximum) reported rate for each harm considered. Because of limitations and heterogeneity in the data, no formal meta-analysis was performed.ResultsThe search identified 32 articles that reported safety data from 24 cryotherapy and LEEP studies. The combined sample consisted of 6,902 women treated by cryotherapy and 4,524 women treated by LEEP. Most studies were conducted in reference or research settings in Asia and Africa. Short-term harms of cryotherapy and LEEP appeared to be similar to those described in the literature from high-income countries. Information was sparse on HIV-related harms and long-term reproductive outcomes of treatment.ConclusionsWhen performed in resource-limited settings by qualified providers, cryotherapy and LEEP are not associated with excess harm. However, available data are insufficient to propose fully evidence-based protocols for routine screening of HIV-infected women and women of reproductive age.

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Section: Discussionmentioning

confidence: 99%

Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scaling-up of cervical screening programs? A systematic review

et al. 2010

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“…LEEP had a significantly higher cure rate of 96% compared to cryotherapy 88%. 15 The efficacy of cryotherapy was found to be 88% and that of LEEP was 94% which is not significantly different. The overall cure rate of symptoms was 82% and 79% in cryosurgery and LEEP group, respectively.…”

Section: Discussionmentioning

confidence: 81%

The outcome of loop electrosurgical excision procedure following treatment of cervical intra-epithelial neoplasia 2 and 3

Satter¹,

Hoque²,

Hoque³

et al. 2023

Int J Reprod Contracept Obstet Gynecol

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Background: In Bangladesh, loop electrosurgical excision procedure (LEEP) is an ongoing program of government health service for the management of cervical intra-epithelial neoplasia (CIN) 2 and 3. The aim of this study was to evaluate the outcome of loop electrosurgical excision procedure following treatment of cervical intra-epithelial neoplasia 2 and 3. Methods: This descriptive cross-sectional study was conducted in outpatient department (OPD), gynaecology and obstetrics department, Rangpur Medical College Hospital, Rangpur, Bangladesh during the period from July 2011 to June 2012. In total 75 patients, underwent LEEP following treatment of CIN 2 and 3 were selected for this study as study subjects. Data analysis was done by using statistical package for social science (SPSS) 16 version. Results: In this study, majority of the participants were from 30-39 years’ age group which was 57%. Besides this 23%, 19% and 1% patients were from <30, 40-49 and ≥50 age groups respectively. The mean parity of the patients was 3.68 with standard deviation of ±1.31 and range was 1 to 7. In analyzing the parity of the participants, we observed that, in 47% and 24% patients the party were 2 and 3 respectively which were noticeable. Besides these in 11%, 8%, 7%, 1% and 3% cases the parity were found as 1, 4, 5, 6 and 7 respectively. In analyzing the histopathology among patients, we found, 76% cases were with CIN-1 whereas the rest 24% cases were with CIN-2. Conclusions: Cervical cancer is the most common malignancy and a major cause of cancer death among Bangladeshi women. This may be due to lack of awareness, scarce of screening facility, poverty and illiteracy. The LEEP procedure has many advantages including high success rate, low cost and ease of use.

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Disease Persistence in Patients with Cervical Intraepithelial Neoplasia Undergoing Electrosurgical Conization

Costa

Nuzzo

Infante

et al. 2002

Gynecologic Oncology

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Electrosurgical Loop Excision of the Cervix

Cited by 6 publications

References 16 publications

Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scaling-up of cervical screening programs? A systematic review

Are treatments for cervical precancerous lesions in less-developed countries safe enough to promote scaling-up of cervical screening programs? A systematic review

The outcome of loop electrosurgical excision procedure following treatment of cervical intra-epithelial neoplasia 2 and 3

Disease Persistence in Patients with Cervical Intraepithelial Neoplasia Undergoing Electrosurgical Conization

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