Electrospun zein/eudragit nanofibers based dual drug delivery system for the simultaneous delivery of aceclofenac and pantoprazole

Ketoprofen-loaded Eudragit electrospun nanofibers for the treatment of oral mucositis

“…For pure EL, there was a broad endotherm between 50°C and 110°C due to dehydration and a second one ranging from 195°C to 219°C, which may be due to thermal degradation. These findings were consistent with other results documented by Illangakoon et al 45 ES exhibited broad glass transition (Tg) endothermic peaks at 90°C and 230°C as reported by Karthikeyan et al 16 These data confirmed that both ES and EL are amorphous as reported previously.…”

Zein/cellulose acetate hybrid nanofibers: Electrospinning and characterization

“…As expected, the spectrum of Zein showed the characteristic bands corresponding to amide I, II, and III at 1643 (C=O stretching), 1531 (N-H bending and C-N stretching) and 1240 cm -1 , respectively. 2,13 The presence of a higher amount of α-helices secondary structure is confirmed by the symmetrical spectral peak at 1643 cm -1 . 3 However, β-sheets (1614 and 1631 cm -1 ) and β-turns (1662 cm -1 ) were not detected.…”

“…It is the predominant prolamine found in corn protein and one of the main co-products of the bioethanol industry. [8][9][10] A series of previous reports showed that due to its nontoxicity, biodegradability and good biocompatibility, zein is a promising natural polymer for use as a scaffold, 1,11 in drug delivery systems, 12,13 in wound healing 4 and in food packaging. 2 It has been successfully blended with other biopolymers such as silk, 3 collagen, 4 chitosan, 14 polycaprolactone, 15 and poly(L-lactide).…”

Electrospun polyurethane/Eudragit ® L100-55 composite mats for the pH dependent release of paclitaxel on duodenal stent cover application

“…7a-c. All nanofiber composite mats submersed in PBS solution with pH 4 has a release rate with no more than 4% and after 6 h the nanocomposite becomes stable in the PBS solution and 0% release or no detection was noted using HPLC analysis. This is mainly due to the property of Eudragit to be stable under pH 5.5 (Karthikeyan et al, 2012;Khan et al, 1999Khan et al, , 2000Shen et al, 2011). With pH being lower than 5.5 the erosion mechanism of Eudragit L100-55 was halted (Terao et al, 2001).…”