Electrospun Nanofibers for Dual and Local Delivery of Neuroprotective Drugs

Haidar, Mohammad Karim; Timur, Selin Seda; Demirbolat, Gülen Melike; Nemutlu, Emirhan; Gürsoy, R. Neslihan; Ulubayram, Kezban; Öner, Levent; Eroğlu, Hakan

doi:10.1007/s12221-021-0228-2

Cited by 11 publications

(8 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They are scaled-down in one phase without modification. These techniques are important and can achieve particles of various sizes and high stability [76]. Spray drying has been reported to be used to produce dry granules and powders from mixtures of drugs and excipients in the form of a solution or suspension.…”

Section: Drying Processesmentioning

confidence: 99%

Chitosan based-nanoparticles and nanocapsules: Overview, physicochemical features, applications of a nanofibrous scaffold, and bioprinting

Shoueir

El-Desouky

Rashad

et al. 2021

International Journal of Biological Macromolecules

118

View full text Add to dashboard Cite

Section: Drying Processesmentioning

confidence: 99%

Chitosan based-nanoparticles and nanocapsules: Overview, physicochemical features, applications of a nanofibrous scaffold, and bioprinting

Shoueir

El-Desouky

Rashad

et al. 2021

International Journal of Biological Macromolecules

118

View full text Add to dashboard Cite

“…Several studies reported about different applications of the nanofibers in medical sectors, such as Malik et al [37], de Carvalho and Conte-Junior [128], Ghajarieha et al as in the pharmaceutical applications, for example, Imani et al [134], Balusamy et al [135], Dodero et al [136], Kumar et al [137], Haidar et al [138], and Pandey [139], as listed in Table 6. The healing process of bones and tendons is very slow, and depending on the severity of the injures, it takes at least six weeks or more for them to regain normal alignment.…”

Section: Nanofibers For Biomedical Fieldsmentioning

confidence: 99%

Sustainable Applications of Nanofibers in Agriculture and Water Treatment: A Review

et al. 2022

View full text Add to dashboard Cite

Natural fibers are an important source for producing polymers, which are highly applicable in their nanoform and could be used in very broad fields such as filtration for water/wastewater treatment, biomedicine, food packaging, harvesting, and storage of energy due to their high specific surface area. These natural nanofibers could be mainly produced through plants, animals, and minerals, as well as produced from agricultural wastes. For strengthening these natural fibers, they may reinforce with some substances such as nanomaterials. Natural or biofiber-reinforced bio-composites and nano–bio-composites are considered better than conventional composites. The sustainable application of nanofibers in agricultural sectors is a promising approach and may involve plant protection and its growth through encapsulating many bio-active molecules or agrochemicals (i.e., pesticides, phytohormones, and fertilizers) for smart delivery at the targeted sites. The food industry and processing also are very important applicable fields of nanofibers, particularly food packaging, which may include using nanofibers for active–intelligent food packaging, and food freshness indicators. The removal of pollutants from soil, water, and air is an urgent field for nanofibers due to their high efficiency. Many new approaches or applicable agro-fields for nanofibers are expected in the future, such as using nanofibers as the indicators for CO and NH3. The role of nanofibers in the global fighting against COVID-19 may represent a crucial solution, particularly in producing face masks.

show abstract

“…Drug-loaded electrospun neural conduits also hold great attention (Mahumane et al 2020;Haidar et al 2021;Farzamfar et al 2018). In this concept, a gabapentinloaded cellulose acetate/gelatin wet-electrospun scaffold was fabricated for neural tissue regeneration (Farzamfar et al 2018).…”

Section: Nerve Tissue Engineering Scaffoldsmentioning

confidence: 99%

“…In another study, the combined multi-technologies were used to determine the neuroprotective effects of atorvastatin and alpha-lipoic acid as active pharmaceutical ingredients in a composite scaffold. The effective scaffolds were obtained by embedding atorvastatin-loaded chitosan nanoparticles into alpha-lipoic acid containing PLGA nanofibers to be evaluated in the peripheral nerve injury treatments for local delivery of neuroprotective drugs (Haidar et al 2021).…”

Section: Nerve Tissue Engineering Scaffoldsmentioning

confidence: 99%

Electrospun Porous Biobased Polymer Mats for Biomedical Applications

Parın

Terzioğlu

2021

Advanced Functional Porous Materials

View full text Add to dashboard Cite

The electrospinning method provides fabrication of nonwoven mats from nano to micrometers in size with controllable pores. Porous electrospun scaffolds have attracted increasing attention in biomedical applications especially due to their ability to mimic the extracellular matrix. This chapter presents a comprehensive overview of the advancements in the last five years through the design and preparation of porous biobased polymer mats using the electrospinning method for biomedical applications. Firstly, fundamentals of the electrospinning process are presented and followed by a discussion of the possible biomedical applications of micro-and nanostructured porous mats for drug delivery, wound dressing, tissue engineering, and other applications. Various crucial points for limitations and possible future trends are presented.

show abstract

Electrospun Nanofibers for Dual and Local Delivery of Neuroprotective Drugs

Cited by 11 publications

References 40 publications

Chitosan based-nanoparticles and nanocapsules: Overview, physicochemical features, applications of a nanofibrous scaffold, and bioprinting

Chitosan based-nanoparticles and nanocapsules: Overview, physicochemical features, applications of a nanofibrous scaffold, and bioprinting

Sustainable Applications of Nanofibers in Agriculture and Water Treatment: A Review

Electrospun Porous Biobased Polymer Mats for Biomedical Applications

Contact Info

Product

Resources

About