2022
DOI: 10.1021/acsabm.2c00496
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Electrospun Magnetic Composite Poly-3-hydroxybutyrate/Magnetite Scaffolds for Biomedical Applications: Composition, Structure, Magnetic Properties, and Biological Performance

Abstract: Magnetically responsive composite polymer scaffolds have good potential for a variety of biomedical applications. In this work, electrospun composite scaffolds made of polyhydroxybutyrate (PHB) and magnetite (Fe 3 O 4 ) particles (MPs) were studied before and after degradation in either PBS or a lipase solution. MPs of different sizes with high saturation magnetization were synthesized by the coprecipitation method followed by coating with citric acid (CA). Nanosized MPs were prone to magnetite−maghemite phase… Show more

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Cited by 16 publications
(22 citation statements)
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“…The microstructures of the scaffolds were studied by performing WLM and SEM using a stereomicroscope Nikon SMZ1500 (Nikon, Tokyo, Japan) and a scanning electron microscope JSM-6380LA (JEOL, Tokyo, Japan), respectively. The scaffolds with attached MSCs and 3T3 cells were also examined using SEM with the special pretreatment of specimens as previously reported [ 16 ].…”
Section: Materials and Methodsmentioning
confidence: 99%
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“…The microstructures of the scaffolds were studied by performing WLM and SEM using a stereomicroscope Nikon SMZ1500 (Nikon, Tokyo, Japan) and a scanning electron microscope JSM-6380LA (JEOL, Tokyo, Japan), respectively. The scaffolds with attached MSCs and 3T3 cells were also examined using SEM with the special pretreatment of specimens as previously reported [ 16 ].…”
Section: Materials and Methodsmentioning
confidence: 99%
“…The 3T3 cells (Biolot, Sankt-Peterburg, Russia) were maintained in DMEM, supplemented with 10% FBS and 50 U/mL penicillin/streptomycin. The bone marrow MSCs were isolated from the femurs of young (3–8 days old) Wistar rats as previously described [ 16 , 43 ]. The isolated MSCs were cultured for 2 weeks in -MEM (PanEco, Moscow, Russia) supplemented with 10% fetal calf serum (FCS, Biological Industries, Beit Haemek, Israel), 50 U/mL penicillin/streptomycin.…”
Section: Materials and Methodsmentioning
confidence: 99%
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