Electrospun chitosan/hydroxyapatite nanofibers for bone tissue engineering

γ-Fe2O3 nanoparticles filled polyvinyl alcohol as potential biomaterial for tissue engineering scaffold

“…The fibers fabricated have similar dimension with the extracellular matrix of human tissue with critical structural and instructive component almost replicating the structure of natural human tissue (Hong Thien et al, 2012;Nelson et al, 2012;Rainer et al, 2011;Sill and von Recum, 2008;Vaquette and CooperWhite, 2013). The fabricated nanofibers tend to favor cell adhesion, proliferation, migration, and differentiation due to the high surface area to volume ratio of the nanofibers combined with the microporous structure; all of them are highly desired properties for tissue engineering applications (Bhattarai et al, 2004;Liao et al, 2008).…”

Electrospun silver ion-loaded calcium phosphate/chitosan antibacterial composite fibrous membranes for guided bone regeneration

“…18,19 CS has attracted great research interest in the biomedical field because of its excellent performance of biocompatibility, blood compatibility, biosecurity, and microbial degradability. [20][21][22][23] Silver ions (Ag + ) as antibacterial agents have broad-spectrum antibacterial properties, and their resistance to bacteria has rarely been reported relative to traditional antibiotics. [24][25][26] Therefore, Ag + and silver nanoparticles have been extensively studied in the medical field.…”

Bioactivity, biocompatibility and antimicrobial properties of a chitosan-mineral composite for periodontal tissue regeneration

“…It is non-toxic, biodegradable, biocompatible, bioactive, non-antigenic, antimicrobial and finds current biomedical application in wound dressings and medical textiles [5][6][7][8][9] . It is a basic linear co-polymer of glucosamine and N-acetylglucosamine whose structure resembles that of bone extracellular matrix (ECM) [10,11] . In comparison with traditional treatment, the application of bioresorbable chitosan-based GTR membranes has been shown to successfully promote the regeneration of the tooth attachment tissues in canine models [12][13][14] .…”

“…It is also prone to bacterial biofilm formation. Previous studies have indicated that blending chitosan with finely divided bioactive and antibacterial phases, such as bioactive glasses, calcium phosphate minerals and silver nanoparticles can enhance bone tissue regeneration and reduce bacterial biofilm formation [11,15,16] .…”