“…Synthetic polymers that are most often used in bone tissue engineering are poly(lactide‐co‐glycolide) (PLGA) (Guo, Du, Wang, Cai, & Yang, 2020), polycaprolactone (PCL) (Liu et al, 2020), poly(vinyl alcohol) (PVA) (Januariyasa et al, 2020), poly(glycolic acid) (PGA) (Takahashi, Yamaguchi, Tanimoto, Yao‐Umezawa, & Kasai, 2015), poly(lactic acid) (PLA) (Behera, Sivanjineyulu, Chang, & Chiu, 2018; Zhang et al, 2020). Chitosan (CS) is intensively investigated in the field of tissue engineering due to its unique properties, such as biodegradability, biocompatibility, adhesiveness and intrinsic antibacterial properties (Hurt, Kotha, Trivedi, & Coleman, 2015; Stevanović et al, 2018). It is very important to point out that chitosan can mimic the structure of glycosaminoglycans in the bone extracellular matrix, contributing to the sponginess of the developed bone (Candy & Sharma, 1990; Francis Suh & Matthew, 2000).…”