Electrospinning: The State of Art Technique for the Production of Nanofibers and Nanofibrous Membranes for Advanced Engineering Applications

Das, Akhila; Balakrishnan, Neethu T. M.; Joyner, Jarin; Medhavi, Nikhil; Manaf, O.; Fatima, Maryam; Ahn, Jin-Hee; Ali, Wazed; Raghavan, Praveen

doi:10.1007/978-981-15-8844-0_2

Cited by 4 publications

(5 citation statements)

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“…Electro Spinning: The versatile and revolutionary method of producing polymer-based high-quality nano-fibers 42 , is a frequently used technique and one of the most promising scaffold-fabricating technique 43 . It includes advantages of ultra-thin film deposition of biomaterials both organic and inorganic due to increased surface area, bioactive material delivery, safety and greater productivity [44][45][46] . The electric field deposits the material as the surface tension of the melt (polymers) is surmounted by the pulling nature of the electric field, leading to evaporation of the solvent 47 .…”

Section: Freeze Dying Methods or Thermally Induced Phase Separation (...mentioning

confidence: 99%

Alveolar Bone Regeneration Via Utilization of Nanohydroxyapatite Scaffolds: A Review

2022

PJMD

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The complete architectural and functional rehabilitation of periodontium owes to the integrity of alveolar bone. The inherent shortcomings of traditional gold standard regenerative procedures like autografting, xenografting, allografting and alloplasting lead to the evolutionary combination of Tissue Engineering/Regenerative Medicine (TE/RM) and nanotechnology for bone repair. Nanotechnology enables the fabrication of either nanoparticles, nanofibers or nanocomposites based on three-dimensional scaffolds. However, it will incorporate vital cells and growth factors in various combinations, to simulate a conducive oral environment of the extracellular matrix (ECM) and empower cells in the bone to regulate in-vivo osteogenesis. The advantageous combination of structural similarity of nanohydroxyapatite (nHA) Scaffolds to the alveolar bone with favorable particle size, response rate, tissue factors and bio factor, makes it attractive for TE/RM. Relevant keywords from 2010-2021 studies were used to retrieve data from "PubMed" and "Google Scholar". This review aims to summarize the cumulative knowledge of commercially available nanohydroxyapatite scaffolds for utilization in alveolar bone augmentation, regeneration of implant osteointegration by their fabrication techniques, advantages, components, types, interaction with various components and particular application of each type for in vivo alveolar bone regeneration. Therefore, nHA scaffolds possess significant osteoconductive and osteoinductive effects on structural similarities to the composition, adhesion and differentiation of bone-forming cells.

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Section: Freeze Dying Methods or Thermally Induced Phase Separation (...mentioning

confidence: 99%

Alveolar Bone Regeneration Via Utilization of Nanohydroxyapatite Scaffolds: A Review

2022

PJMD

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“…2(a), the basic components of an electrospinning unit are a high voltage power supply, spinning unit (syringe and pump) and grounded collector. 57,58 During the process, a high DC voltage is applied between the collector and spinneret, which will be responsible for forming a Taylor cone of the spinning solution at the tip of the needle. The Taylor cone will elongate into the collector as a fiber mat when the solution overcomes the electrostatic force.…”

Section: Fundamentals Of Electrospinningmentioning

confidence: 99%

Recent advances in electrospun fibers based on transition metal oxides for supercapacitor applications: a review

et al. 2023

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“…Electrospinning involves the production of continuous fibers from inducing the charged filaments of polymer solutions by using an electric force directed by a highvoltage system equipped with a syringe connected to a metallic needle, a pressure pump, and a grounded stationary or rotating collector [81][82][83]. The liquid solution, pumped into the syringe, flows up to onto a pendent droplet suspended at the needle tip, which is then stretched continuously to form a cone-like structure, called the Taylor cone, while increasing the applied voltage.…”

Section: Electrospinningmentioning

confidence: 99%

“…Polymers 2021, 13, x 10 of 21 is continuously stretched and thinned down by the electrostatic force overcoming the liquid surface tension [81]. The electrospinning process requires particular attention to factors influencing the structure and size of electrospun fibers and preventing the break-up of the fibers during the process, such as solution concentration, polymer average molecular weight and distribution, viscosity, electric field, solution feed rate, and voltage [84].…”

Section: Electrospinningmentioning

confidence: 99%

“…The liquid solution, pumped into the syringe, flows up to onto a pendent droplet suspended at the needle tip, which is then stretched continuously to form a cone-like structure, called the Taylor cone, while increasing the applied voltage. Successive jet initiates from the tip of the Taylor cone, and then it is continuously stretched and thinned down by the electrostatic force overcoming the liquid surface tension [ 81 ]. The electrospinning process requires particular attention to factors influencing the structure and size of electrospun fibers and preventing the break-up of the fibers during the process, such as solution concentration, polymer average molecular weight and distribution, viscosity, electric field, solution feed rate, and voltage [ 84 ].…”

Section: Electrospinningmentioning

confidence: 99%

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Solution-Based Processing for Scaffold Fabrication in Tissue Engineering Applications: A Brief Review

et al. 2021

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The fabrication of 3D scaffolds is under wide investigation in tissue engineering (TE) because of its incessant development of new advanced technologies and the improvement of traditional processes. Currently, scientific and clinical research focuses on scaffold characterization to restore the function of missing or damaged tissues. A key for suitable scaffold production is the guarantee of an interconnected porous structure that allows the cells to grow as in native tissue. The fabrication techniques should meet the appropriate requirements, including feasible reproducibility and time- and cost-effective assets. This is necessary for easy processability, which is associated with the large range of biomaterials supporting the use of fabrication technologies. This paper presents a review of scaffold fabrication methods starting from polymer solutions that provide highly porous structures under controlled process parameters. In this review, general information of solution-based technologies, including freeze-drying, thermally or diffusion induced phase separation (TIPS or DIPS), and electrospinning, are presented, along with an overview of their technological strategies and applications. Furthermore, the differences in the fabricated constructs in terms of pore size and distribution, porosity, morphology, and mechanical and biological properties, are clarified and critically reviewed. Then, the combination of these techniques for obtaining scaffolds is described, offering the advantages of mimicking the unique architecture of tissues and organs that are intrinsically difficult to design.

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Electrospinning: The State of Art Technique for the Production of Nanofibers and Nanofibrous Membranes for Advanced Engineering Applications

Cited by 4 publications

References 133 publications

Alveolar Bone Regeneration Via Utilization of Nanohydroxyapatite Scaffolds: A Review

Alveolar Bone Regeneration Via Utilization of Nanohydroxyapatite Scaffolds: A Review

Recent advances in electrospun fibers based on transition metal oxides for supercapacitor applications: a review

Solution-Based Processing for Scaffold Fabrication in Tissue Engineering Applications: A Brief Review

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