Electrospinning approach for nanoencapsulation of bioactive compounds; recent advances and innovations

Rostamabadi, Hadis; Assadpour, Elham; Tabarestani, Hoda Shahiri; Falsafi, Seid Reza; Jafari, Seid Mahdi

doi:10.1016/j.tifs.2020.04.012

Cited by 102 publications

(25 citation statements)

References 160 publications

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“…However, there are manufacturing difficulties associated with the bioactive electrospun nanofibers. For example, the ability of electrospinning of pure proteins is limited due to the complex secondary and tertiary configurations, although proteins have been promising biopolymers for electrospun fiber generation [ 90 ]. The manufacturability of bioactive electrospun nanofibers is listed in Table 4 .…”

Section: Electrospun Ultrafine Fibers For Reusable Face Masksmentioning

confidence: 99%

Electrospun ultrafine fibers for advanced face masks

Zhang

et al. 2021

Materials Science and Engineering: R: Reports

128

119

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The outbreak of Coronavirus Disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has triggered great global public health concern. Face masks are essential tools to reduce the spread of SARS-CoV-2 from human to human. However, there are still challenges to prolong the serving life and maintain the filtering performance of the current commercial mask. Filters composed of ultrafine fibers with diameter down to tens of nanometers have the potential to physically block viruses. With adjustable composition and nanostructures, the electrospun ultrafine fiber filter is possible to achieve other necessary functions beyond virus blocking, such as antiviral, transparent, and degradable, making it an important part of fighting the epidemic. In this review, beginning with the basic information of the viruses, we summarize the knowledge of masks and respirators, including the filtering mechanism, structure, classification, and standards. We further present the fabrication method, filtering performance, and reusable potential of electrospun ultrafine fiber-based masks. In the end, we discuss the development directions of ultrafine fibers in protective devices, especially their new functional applications and possible contributions in the prevention and control of the epidemic.

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Section: Electrospun Ultrafine Fibers For Reusable Face Masksmentioning

confidence: 99%

Electrospun ultrafine fibers for advanced face masks

Zhang

et al. 2021

Materials Science and Engineering: R: Reports

128

119

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“…Bioactive lipids can be directly or indirectly trapped within the biopolymer solution used to form the nanofibers prior to the electrospinning process. Nanochitin, nanocellulose, and nano-starch delivery systems have been produced using this method for food processing and packaging applications [ 48 , 49 ].…”

Section: Nanoscale Delivery Systems For Encapsulation Of Bioactivementioning

confidence: 99%

Utilization of Nanotechnology to Improve the Handling, Storage and Biocompatibility of Bioactive Lipids in Food Applications

McClements

Öztürk

2021

Foods

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Bioactive lipids, such as fat-soluble vitamins, omega-3 fatty acids, conjugated linoleic acids, carotenoids and phytosterols play an important role in boosting human health and wellbeing. These lipophilic substances cannot be synthesized within the human body, and so people must include them in their diet. There is increasing interest in incorporating these bioactive lipids into functional foods designed to produce certain health benefits, such as anti-inflammatory, antioxidant, anticancer and cholesterol-lowering properties. However, many of these lipids have poor compatibility with food matrices and low bioavailability because of their extremely low water solubility. Moreover, they may also chemically degrade during food storage or inside the human gut because they are exposed to certain stressors, such as high temperatures, oxygen, light, moisture, pH, and digestive/metabolic enzymes, which again reduces their bioavailability. Nanotechnology is a promising technology that can be used to overcome many of these limitations. The aim of this review is to highlight different kinds of nanoscale delivery systems that have been designed to encapsulate and protect bioactive lipids, thereby facilitating their handling, stability, food matrix compatibility, and bioavailability. These systems include nanoemulsions, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), nanoliposomes, nanogels, and nano-particle stabilized Pickering emulsions.

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“…Electrospinning was successfully tested to obtain various polymeric materials for food packaging, either by entrapping of bioactive agents or by deposition of electrospun fibers as coatings onto polymeric films to structure the surface and to confer desired functionalities [23]. In particular, the development of new formulations by nanoencapsulation of various bioactive compounds was recently exploited for delivery of nutraceuticals in foods [24]. Recent research reports on active packaging obtained by incorporation of vanillin or quercetin as natural active agents into zein fibers prepared by combining electrospinning and supercritical fluids impregnation [25] or encapsulated in cyclodextrin inclusion complex [26].…”

Section: Introductionmentioning

confidence: 99%

Bioactive Electrospun Fibers of Poly(ε-Caprolactone) Incorporating α-Tocopherol for Food Packaging Applications

Dumitriu¹,

Stoleru²,

Mitchell

et al. 2021

Molecules

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Antioxidant activity is an important feature for food contact materials such as packaging, aiming to preserve freshness and retard food spoilage. Common bioactive agents are highly susceptible to various forms of degradation; therefore, protection is required to maintain functionality and bioavailability. Poly(ε-caprolactone) (PCL), a biodegradable GRAS labeled polymer, was used in this study for encapsulation of α-tocopherol antioxidant, a major component of vitamin E, in the form of electrospun fibers. Rheological properties of the fiber forming solutions, which determine the electrospinning behavior, were correlated with the properties of electrospun fibers, e.g., morphology and surface properties. Interactions through hydrogen bonds were evidenced between the two components. These have strong effect on structuration of macromolecular chains, especially at low α-tocopherol amounts, decreasing viscosity and elastic modulus. Intra-molecular interactions in PCL strengthen at high α-tocopherol amounts due to decreased solvation, allowing good structural recovery after cease of mechanical stress. Morphologically homogeneous electrospun fibers were obtained, with ~6 μm average diameter. The obtained fibers were highly hydrophobic, with fast release in 95% ethanol as alternative simulant for fatty foods. This induced good in vitro antioxidant activity and significant in vivo reduction of microbial growth on cheese, as determined by respirometry. Therefore, the electrospun fibers from PCL entrapping α-tocopherol as bioactive agent showed potential use in food packaging materials.

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Electrospinning approach for nanoencapsulation of bioactive compounds; recent advances and innovations

Cited by 102 publications

References 160 publications

Electrospun ultrafine fibers for advanced face masks

Electrospun ultrafine fibers for advanced face masks

Utilization of Nanotechnology to Improve the Handling, Storage and Biocompatibility of Bioactive Lipids in Food Applications

Bioactive Electrospun Fibers of Poly(ε-Caprolactone) Incorporating α-Tocopherol for Food Packaging Applications

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