Electropolymerization of bromothymol blue on carbon paste electrode bulk modified with oxidized multiwall carbon nanotubes and its application in amperometric sensing of epinephrine in pharmaceutical and biological samples

Pradhan, Prerna; Mascarenhas, Ronald J.; Thomas, Tony; Namboothiri, Irishi N. N.; D’Souza, Ozma J.; Mekhalif, Zineb

doi:10.1016/j.jelechem.2014.08.023

Cited by 38 publications

(20 citation statements)

References 59 publications

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“…In our continual effort to employ CPE and modified CPE for electroanalytical applications [31][32][33][34][35][36][37][38], in the present work, our aim was to fabricate a non-enzymatic sensor for Tyr. To achieve this, we have modified CPE by bulk modifying it using COOH-MWCNTs in the CPE matrix and employed it for the sensitive determination of Tyr in the presence of interfering molecules.…”

Section: Introductionmentioning

confidence: 99%

Electrocatalytic oxidation of l-tyrosine at carboxylic acid functionalized multi-walled carbon nanotubes modified carbon paste electrode

D’Souza

Mascarenhas

Satpati

et al. 2015

Ionics

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The electrocatalytic oxidation of L-tyrosine (Tyr) was investigated on a carboxylic acid functionalised multiwalled carbon nanotubes modified carbon paste electrode using cyclic voltammetry and amperometry. The surface morphology of the electrodes was studied using field emission (FE)-SEM images, and the interface properties of bare and modified electrodes were investigated by electrochemical impedance spectroscopy (EIS). The influence of the amount of modifier loading and the variation of the pH of the solution on the electrochemical parameters have been investigated. Cyclic voltammetry was carried out to study the electrochemical oxidation mechanism of Tyr, which showed an irreversible oxidation process at a potential of 637.0 mV at modified electrode. The anodic peak current linearly increased with the scan rate, suggesting that the oxidation of Tyr at modified electrode is an adsorption-controlled process. A good linear relationship between the oxidation peak current and the Tyr concentration in the range of 0.8-100.0 μM was obtained in a phosphate buffer solution at pH 7.0 with a detection limit of 14.0± 1.36 nM (S/N=3). The practical utility of the sensor was demonstrated by determining Tyr in spiked cow's milk and human blood serum. The modified electrode showed excellent reproducibility, long-term stability and antifouling effects.

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Section: Introductionmentioning

confidence: 99%

Electrocatalytic oxidation of l-tyrosine at carboxylic acid functionalized multi-walled carbon nanotubes modified carbon paste electrode

D’Souza

Mascarenhas

Satpati

et al. 2015

Ionics

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“…In another study, Pradhan et al [71] employed a composite electrode for the amperometric detection of EP. Composite electrode was developed by electropolymerizing bromothymol blue (BTB) on the CPE bulk modified with MWCNTs.…”

Section: Modified Electrodes With Carbon Nanotubesmentioning

confidence: 99%

Voltammetric and amperometric sensors for determination of epinephrine: A short review (2013-2017)

Beitollahi

Safaei

Tajik

2018

J. Electrochem. Sci. Eng.

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<p><span lang="EN-US">The present review focuses on voltammetric and amperometric methods applied for determination of epinephrine (EP) in last five years (2013-2017). Occurrence, role and biological importance of EP, as well as non-electrochemical methods for its assessment, are firstly reviewed. The electrochemical behavior of EP is then illustrated, followed by a description of the voltammetric and amperometric methods for EP content estimation in various media. Different methods for development of electrochemical sensors are reviewed, starting from unmodified electrodes to different composites incorporating carbon nanotubes, ionic liquids or various mediators. From this perspective, the interaction between functional groups of the sensor material and the analyte molecule is discussed, as it is essential for analytical characteristics obtained. The analytical performances of the voltammetric or amperometric chemical and biochemical sensors (linear range of analytical response, sensitivity, precision, stability, response time, etc.) are highlighted. Numerous applications of EP electrochemical sensors in fields like pharmaceutical or clinical analysis where EP represents a key analyte, are also presented.</span></p>

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“…The electro chemical methods using chemically modified electrode have been widely used in sensitive and selective analytical methods for the detection of the trace amounts of biologically important compounds [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Zinc Metal at a New ZnO Nanoparticles Modified Carbon Paste Electrode: A Cyclic Voltammetric Study

Abood¹,

Jouda²,

Mashkoor³

2018

Nano BioMed ENG

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A new carbon paste electrode modified with ZnO nanoparticles was prepared and used to study the electro oxidation of zinc ions in solution by cyclic voltammetry (CV) method. The modified electrode displayed strong resolving function for the overlapping voltammetric response of zinc into one welldefined peak. The potential difference between Epa and Epc was > 200 mV, the range of which referred to the quasi-reversible mechanism. The kinetic of electrode was studied in the range of temperature 15-30 °C. The data of voltamograms showed the negative shift increased with increase of temperature, the result of which referred to the diffusion electron transfer in redox process of zinc oxidation. Diffusion coffining was calculated from Sevcik-Randles equation and thus equaled to 1.01×10-7. The rate constant was equal to 5.2×10-8 and 3.3×10-8 for oxidation and redaction respectively. And the peak current of zinc increased linearly with its concentration in the range of 2.0-20.0 ppm.

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Electropolymerization of bromothymol blue on carbon paste electrode bulk modified with oxidized multiwall carbon nanotubes and its application in amperometric sensing of epinephrine in pharmaceutical and biological samples

Cited by 38 publications

References 59 publications

Electrocatalytic oxidation of l-tyrosine at carboxylic acid functionalized multi-walled carbon nanotubes modified carbon paste electrode

Electrocatalytic oxidation of l-tyrosine at carboxylic acid functionalized multi-walled carbon nanotubes modified carbon paste electrode

Voltammetric and amperometric sensors for determination of epinephrine: A short review (2013-2017)

Zinc Metal at a New ZnO Nanoparticles Modified Carbon Paste Electrode: A Cyclic Voltammetric Study

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