Electrophoretic separations of twelve phenothiazines and N-demethyl derivatives by using capillary zone electrophoresis and micellar electrokinetic chromatography with non ionic surfactant

MEKC: An update focusing on practical aspects

“…Neutral micelles can also be used to separate charged compounds, but few applications of this nature have been reported in recent years. Le et al [139] accomplished the separation of phenothiazines and their N-demethyl metabolites by MEKC, using a BGE containing phosphoric acid at pH 2.5 and octaethylene glycol monododecyl ether as a nonionic surfactant with the same alkyl chain length as SDS. Further, Li et al [140] developed a novel assay method for the determination of the theanine synthetase activity by using a BGE containing Brij-35 and isopropanol at pH 9.8.…”

Promethazine determination in plasma samples by using carbon paste electrode modified with molecularly imprinted polymer (MIP): Coupling of extraction, preconcentration and electrochemical determination

“…In practice, numerous procedures such as oxidation titrations [3][4][5][6][7][8], spectrophotometry [9][10][11][12][13][14][15][16], chemiluminescence [17], turbidimetry [18], capillary electrophoresis [19,20] and gas chromatography [21,22] have been employed to determine promethazine. HPLC methods are now widely used for promethazine determination [23][24][25][26][27].…”

Enantioseparation of phenothiazines in CD‐modified CZE using single isomer sulfated CD as a chiral selector

“…1. Phenothiazines and the enantiomers as well have previously been separated by CE [41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58], mostly by CZE [41,[43][44][45][46][47][48][49][50][52][53][54][55][56][57]. The applications of the CE technique to the enantioseparations of phenothiazines using CDs as chiral selectors have been reported [41,42,47,48,[50][51][52][53][54].…”