Electrophoretic Protein and Amino Acid Analysis of Lucilia sericata, Chrysomya albiceps (Diptera: Calliphoridae) And Musca domestica (Diptera: Muscidae) Larval Excretion/Secretion

Antimicrobial and antiviral activity of maggots extracts of Lucilia sericata (Diptera: Calliphoridae)

“…Lucilia sericata maggots' extracts was more effective than those of C. albiceps, S. carnaria and M. domestica as recorded by Thomas et al (1999), where L. sericata larvae were able to decrease the total bacterial count of S. aureus in vitro and to combat clinical infections in a variety of wound types including these caused by antibiotic-resistant strains. Such findings may be due to the presence of antibacterial agents in their secretion/excretion (Amer et al 2019b).…”

“…The obtained results revealed also that petroleum ether extract of L. sericata recorded promising activity as antiHSV-1. The same results were reported by Esser et al (1979), for treatment of murine virus capsid with melittin; Wachinger et al (1998) who stated that, the reduction of viral infectivity is not due to an effect of melittin on the virus particles but to an intracellular action of the peptide that readily taken up into the cells; Baier et al (2000) who found that, nasal application of lipopeptide increased protection against the lethal infection of influenza; Fenard et al, (2001) who found that, the honeybee venom inhibits the replication of Tlymphotropic HIV-1 isolates; Chernysh et al (2002) who tested the activity of alloferon against Herpes Simplex and Hepatitis B and C infection; Slocinska et al (2008) who stated that, insects originally owned Cecropins and melittin peptides that able to cause antiviral action against HSV; Ai et al (2008) who found that, the protein fractions extracted and purified from the larvae of the housefly possess antiviral activity; Also, Amer et al (2019b) reported that, L. sericata, C. albiceps and M. domestica secretion/excretion and maggots' whole body extracts recorded antiviral activity against Hepatitis A Virus (HAV).…”