Electron paramagnetic resonance radiation dosimetry in fingernails

Trompier, F.; Romanyukha, Alexander; Kornak, L.; Calas, C.; LeBlanc, B.; Mitchell, C. A.; Swartz, Harold M.; Clairand, I.

doi:10.1016/j.radmeas.2008.10.005

Cited by 52 publications

(41 citation statements)

References 10 publications

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“…Significant progress in the development of electron paramagnetic resonance (EPR) dosimetry in fingernails has been achieved in recent years (see Reyes et al, 2008Reyes et al, , 2009Romanyukha et al, 2007bRomanyukha et al, , 2010Trompier et al, 2007Trompier et al, , 2009. Chemically, fingernails are mainly composed of alpha keratin, a protein made of three alpha helical peptide chains, twisted in a left-handed coil that is strengthened by disulfide bridges from adjacent cystein groups.…”

Section: Introductionmentioning

confidence: 99%

EPR measurements of fingernails in Q-band

Romanyukha¹,

Trompier

Reyes

et al. 2011

Radiation Measurements

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a b s t r a c tResults of a feasibility study for the use of the Q-band EPR measurements of fingernails are presented. Details of the first protocol developed for Q-band (34 GHz) EPR dose measurements in fingernails and preliminary results of a dosimetry study in comparison with the commonly-used X-band (9 GHz) are reported. It was found that 1e5 mg sample mass was sufficient for EPR measurements in fingernails in the Q-band, which is significantly less than the 15e30 mg needed for the X-band. This finding makes it possible to obtain sufficient fingernail sample for dose measurements, practically from every finger of any person. Another finding was that the spectral resolution of the mechanically-induced signal (MIS) and radiation-induced signal (RIS) in the Q-band was significantly better than in the X-band. The RIS and MIS in the Q-band spectrum have a more complex structure than in the X-band, which potentially offers the possibility to do dose measurements in fingernails without treatment and immediately after clipping. These findings and recent results related to fingernail dosimetry in the Q-band and its perspectives are discussed here.Published by Elsevier Ltd.

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Section: Introductionmentioning

confidence: 99%

EPR measurements of fingernails in Q-band

Romanyukha¹,

Trompier

Reyes

et al. 2011

Radiation Measurements

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“…All were seen to reduce the MIS signal. Trompier et al (2009b) observed that "painting" the edge of the cut fingernail with water significantly, but not completely, reduced the MIS. Soaking in water has been adopted by many authors (Reyes et al, 2008.…”

Section: Protocols For Dose Assessmentmentioning

confidence: 96%

“…Although the use of fingernails as potential radiation dosimeters was suggested as early as the late 1980s (Chandra andSymons, 1987 andDalgarno andMcClymont, 1989) it is only in more recent years that significant effort has been devoted to the development of an EPR technique for fingernails as an emergency dosimetry method, especially through the work of Trompier, Romanyukha and others (e.g., Trompier et al, 2009a, Trompier et al, 2009band Black and Swarts, 2010. See also a recent review by Marciniak and Ciesielski, 2016.).…”

Section: Radiation-induced Radicalsmentioning

confidence: 99%

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Retrospective and emergency dosimetry in response to radiological incidents and nuclear mass-casualty events: A review

Bailiff

Sholom

McKeever

2016

Radiation Measurements

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Additional information:Use policyThe full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-prot purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details. HIGHLIGHTSReview of the use of luminescence and electron paramagnetic resonance in retrospective and emergency dosimetry.Optically stimulated luminescence (OSL), thermoluminescence (TL) and Electron Paramagnetic Resonance (EPR) results on biological and physical materials.Descriptions of use in emergency and retrospective dosimetry, following large-scale radiological events.http://www.sciencedirect.com/science/article/pii/S1350448716302359 ABSTRACTThis paper reviews recent research on the application of the physical dosimetry techniques of electron paramagnetic resonance (EPR) and luminescence (optically stimulated luminescence, OSL, and thermoluminescence, TL) to determine radiation dose following catastrophic, large-scale radiological events. Such data are used in dose reconstruction to obtain estimates of dose due to the exposure to external sources of radiation, primarily gamma radiation, by individual members of the public and by populations. The EPR and luminescence techniques have been applied to a wide range of radiological studies, including nuclear bomb detonation (e.g., Hiroshima and Nagasaki) nuclear power plant accidents (e.g., Chernobyl), radioactive pollution (e.g., Mayak plutonium facility), and in the future could include terrorist events involving the dispersal of radioactive materials. In this review we examine the application of these techniques in 'emergency' and 'retrospective' modes of operation that are conducted on two distinct timescales. For emergency dosimetry immediate action to evaluate dose to individuals following radiation exposure is required to assess deterministic biological effects and to enable rapid medical triage. Retrospective dosimetry, on the other hand, contributes to the reconstruction of doses to populations and individuals following external exposure, and contributes to the long-term study of stochastic processes and the consequential epidemiological effects. Although internal exposure, via ingestion of radionuclides for example, can be a potentially significant contributor to dose, this review is confined to those dose components arising from exposure to external radiation, which in most studies is gamma radiation.The nascent emergency dosimetry measurement techniques aim to perform direct dose evaluations for individuals who, as members of the public, are most unlikely to be carrying a dosimeter issued for radiation monitoring purposes in the event of a radiation incident. Hence attention has focused on b...

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“…There is renewed interest in quantitation of these electron paramagnetic resonance (EPR) signals because of their potential utility for measuring radiation dose, especially for medical triage in situations where there is a need to determine whether large numbers of people were exposed to medically significant doses of radiation (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13) . Fingernail dosimetry has been applied to three cases of accidental radiation exposure (14) .…”

Section: Introductionmentioning

confidence: 99%

Comparison of Continuous Wave and Rapid Scan X-band Electron Paramagnetic Resonance of Irradiated Clipped Fingernails

Elajaili

McPeak

Romanyukha³

et al. 2016

Radiat Prot Dosimetry

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X-band rapid scan electron paramagnetic resonance (EPR) measures the free radicals in irradiated clipped fingernails with higher signal-to-noise (S/N) and lower standard deviation of the signal amplitude for replicate measurements than does conventional continuous wave (CW) EPR in the same measurement time. For a clipped fingernail sample irradiated to 10 Gy and data acquisition time of 30 s with B 1 = 8.5 μT, the S/N for rapid scan is >2000 for the absorption spectrum and 1200 for the corresponding first derivative. The standard deviation for replicate measurements of signal amplitude is~1%. For CW spectra, the S/N depends on the modulation amplitude. The CW signal has a first derivative peak-to-peak linewidth of 0.95 mT. For 30 s of CW acquisition time, the S/N was 30 for a conservative modulation amplitude of 0.2 mT and B 1 of 2.3 μT or 90 for a modulation amplitude of 0.4 mT and B 1 of 3.2 μT, which resulted in standard deviations of replicate measurements of 5% or 2%, respectively.

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Electron paramagnetic resonance radiation dosimetry in fingernails

Cited by 52 publications

References 10 publications

EPR measurements of fingernails in Q-band

EPR measurements of fingernails in Q-band

Retrospective and emergency dosimetry in response to radiological incidents and nuclear mass-casualty events: A review

Comparison of Continuous Wave and Rapid Scan X-band Electron Paramagnetic Resonance of Irradiated Clipped Fingernails

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