Electron microscopic studies on the pars intermedia in normal and in mice with hereditary nephrogenic diabetes insipidus

Naik, D. V.

doi:10.1007/bf00307248

Cited by 16 publications

(1 citation statement)

References 22 publications

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“…True corticotrophic cells were described in the IL of rat and mouse hypophysis [Porte et al, 1971;Naik, 1972], In addition, in the mouse, immunological staining for ACTH has been demonstrated only in these corti cotrophic cells [Stoeckel et al, 1973]. Never theless, other immunocytological studies have shown ACTH to be present in all the cells of the IL [see Mialhe and Briaud, 1976] indicating that both ACTH and a-MSH are possibly present in the melanotrophic cells.…”

Section: Resultsmentioning

confidence: 99%

Different Effects of K+ and Ca++ on α-MSH and ACTH Release from Superfused Neurointermediate Lobe of the Rat Hypophysis

Schmitt¹,

Briaud²,

Mialhe³

et al. 1979

Neuroendocrinology

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The effects of K⁺-enhanced and Ca⁺⁺-free media on α-MSH and adrenocorticotropic hormone (ACTH) release from superfused neurointermediate lobe (NIL) were studied in the same experiments. High K⁺ caused reversible and repeatable inhibition of α-MSH release and stimulation of ACTH release. Removal of Ca⁺⁺ impaired the effect of K⁺, irreversibly for α-MSH and reversibly for ACTH. The existence of both melanotrophic and corticotrophic cells within the intermediate lobe (IL) of rat hypophysis could account for the different effects of ionic modifications on in vitro α-MSH and ACTH release.

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Section: Resultsmentioning

confidence: 99%