Electron beam modification for improving dose uniformity in irradiated objects

Студеникин, Ф. Р.; Bliznyuk, U. A.; Chernyaev, A. P.; Krusanov, G. A.; Nikitchenko, A. D.; Zolotov, S. A.; Ipatova, V. S.

doi:10.1140/epjs/s11734-023-00886-6

Cited by 4 publications

(5 citation statements)

References 5 publications

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“…This study proposes a method of modifying the beam spectrum using aluminum plates, which allows to increase the dose uniformity during irradiation with accelerated electrons with the energy up to 10 MeV [44]. The main idea of increasing the uniformity of irradiation consists in additional placement of modifier plates between the beam output and the irradiated object.…”

Section: Electron Beam Modification Methods For Improving Dose Unifor...mentioning

confidence: 99%

“…and to calculate with an error not exceeding 5% the irradiation uniformity K for different combinations of modifier thicknesses d in the range from 0.5 mm to 5 mm and initial electron energies E 0 : [44].…”

Section: Electron Beam Modification Methods For Improving Dose Unifor...mentioning

confidence: 99%

“…One of the key factors that lead to the non-uniformity of electron beam irradiation is the character of depth dose distribution, which depends on the energy of electrons. Figure 1a and b shows the dependency of the relative absorbed dose on the penetration depth in water parallelepiped irradiated with 4 MeV, 6 MeV, 8 MeV, and 10 MeV, calculated using the GEANT4 toolkit [44]. Figure 1a shows that the higher the electron energy, the deeper the penetration of electrons into the object is and the lower maximum dose is achieved during irradiation.…”

Section: Electron Beam Energymentioning

confidence: 99%

“…Modern dosimetry methods for determining the integral dose absorbed by an object and its dose distribution during industrial irradiation are time-consuming and expensive [47,48]. Dosimetry requires regular repetition and calibration due to possible changes in the electron beam spectrum during operation of the industrial accelerator [44,49].…”

Section: Computer Simulation Of Depth Dose Distributionsmentioning

confidence: 99%

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Electron Beam Processing of Biological Objects and Materials

Bliznyuk,

Chernyaev,

Ipatova

et al. 2023

Ion Beam Technology and Applications

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The research explores a wide range of applications for electron accelerators in industrial irradiation processing. It also compares the physical properties of electron beams, dose ranges, and methods used for irradiation of polymers, medical items, transplantology objects, pharmaceuticals, and foods. Moreover, the study discusses the depth dose non-uniformity in objects irradiated with accelerated electrons. The research also highlights the dependency of geometry, density, and chemical composition of the object on the dose distribution. Another focus of the study is computer simulation of electron irradiation method, encompassing all physical and technical parameters to assess the dose distribution throughout the irradiated objects, since without knowing the precise electron beam spectrum, it is impossible to accurately reconstruct the dose distribution throughout the objects. Considering that the beam spectrum cannot always be identified, especially for industrial accelerators, the study presents algorithm for reconstructing the dose distribution in irradiated objects. The final part of the research provides methods for increasing the dose uniformity throughout objects irradiated with electron beams.

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Section: Electron Beam Modification Methods For Improving Dose Unifor...mentioning

confidence: 99%

Section: Electron Beam Modification Methods For Improving Dose Unifor...mentioning

confidence: 99%

Section: Electron Beam Energymentioning

confidence: 99%

Section: Computer Simulation Of Depth Dose Distributionsmentioning

confidence: 99%

See 2 more Smart Citations

Electron Beam Processing of Biological Objects and Materials

Bliznyuk,

Chernyaev,

Ipatova

et al. 2023

Ion Beam Technology and Applications

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“…As can be seen, during bilateral irradiation, the maximum dose of 100% is absorbed by the layers at the depth between 1 mm and 2 mm from the surface of the parallelepiped. The relatively low dose uniformity caused by electron beams should be taken into account in the search for optimal food parameters [27].…”

Section: Nonuniformity Of Depth-dose Distribution Across Beef Samplesmentioning

confidence: 99%

Hemoglobin Derivatives in Beef Irradiated with Accelerated Electrons

Bliznyuk,

Borshchegovskaya,

Chernyaev

et al. 2023

Molecules

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The efficiency of food irradiation depends on the accuracy of the irradiation dose range that is sufficient for inhibiting microbiological growth without causing an irreversible change to the physical and chemical properties of foods. This study suggests that the concentration of hemoglobin derivatives can be used as a criterion for establishing the limit for chilled beef irradiation at which irradiation-induced oxidation becomes irreversible. The express spectrophotometry method for estimating the hemoglobin derivative concentration shows a nonlinear increase in methemoglobin concentration from 15% to 50% in beef irradiated by accelerated electrons with the doses ranging from 250 Gy to 10,000 Gy. The monitoring of the hemoglobin derivative concentration for three days after irradiation shows nonmonotonous dependencies of methemoglobin concentration in beef in the storage time since the oxidation of hemoglobin occur as a result of irradiation and biochemical processes in beef during storage. The proposed method based on the quantitative analysis of the hemoglobin derivative concentration can be used to estimate the oxidation level for irradiation of foods containing red blood cells. The study proposes a model that describes the change in hemoglobin derivative concentration in beef after irradiation considering that oxidation of hemoglobin can be triggered by the direct ionization caused by accelerated electrons, biochemical processes as a result of bacterial activity, and reactive oxygen species appearing during irradiation and storage. This research throws light on the mechanisms behind food irradiation during storage that should be taken into account for selecting the optimal parameters of irradiation.

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