“…However, due to the increased muscle effort required to stabilize abnormal postural displacements, the actual increase in load on the spine is much higher [19]. The presence of mechano-sensitive and nociceptive afferent fibers in spinal tissues (intervertebral disc, facet, ligaments, and muscles) [30,42,43,46,50]-and the subsequent neurophysiological research demonstrating the role of such afferent stimulation in pain production [9,10,11] and coordinated neuromuscular stabilization of the spine [28,29,52,53,54,55]-provide a substantial theoretical framework supporting the rationale for goals of treatment regimens to include a reduction of stresses on spinal joints in spinal rehabilitation programs.…”