Electroencephalographic mapping and 99mTc HMPAO single-photon emission computed tomography in carbon monoxide poisoning

Denays, Roger; Makhoul, Elias; Dachy, Bernard; Tondeur, Marianne; Noël, Philippe; Ham, Hamphrey; Mols, Pierre

doi:10.1016/s0196-0644(94)70212-8

Cited by 23 publications

(11 citation statements)

References 18 publications

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“…Except for 1 H-MRS and diffusion-weighted imaging (DWI) used in this study, conventional MRI, EEG, and single-photon emission computed tomography were proposed previously [8,9,10]. However, there were several problems encountered when these techniques were used in our 2 patients.…”

Section: Discussionmentioning

confidence: 99%

Serial Assessments of Delayed Encephalopathy after Carbon Monoxide Poisoning Using Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging on 3.0T System

Terajima¹,

Igarashi²,

Hirose

et al. 2007

Eur Neurol

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To elucidate the still unclear mechanism of delayed encephalopathy after carbon monoxide (CO) poisoning, we serially performed single-voxel proton magnetic resonance spectroscopy (¹H-MRS) and diffusion tensor imaging (DTI) on a 3.0T system and intelligence tests in 2 patients, while they were undergoing hyperbaric oxygenation therapy. The chronological changes in ¹H-MRS- and DTI-derived parameters indicated the following: (1) White matter demyelination, aerobic metabolism inhibition, and cytotoxic edema persisted for at least 3 months even after starting the hyperbaric oxygenation therapy; (2) the axonal function and structural integrity of the white matter were initially severely impaired and then gradually and partially improved for 5 months, showing changes similar to those in the scores of the intelligence tests. The results demonstrated that brain damage after CO poisoning may persist longer than expected, and that the ¹H-MRS- and DTI-derived parameters are good indicators of the clinical progress of a patient. The combination of ¹H-MRS and DTI on a 3.0T system is useful for monitoring the changes in brain damage and the clinical symptoms of patients with delayed encephalopathy after CO poisoning.

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Section: Discussionmentioning

confidence: 99%

Serial Assessments of Delayed Encephalopathy after Carbon Monoxide Poisoning Using Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging on 3.0T System

Terajima¹,

Igarashi²,

Hirose

et al. 2007

Eur Neurol

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“…Single-photon emission CT (SPECT), electroencephalography, and quantitative MRI have been studied as adjunctive diagnostic tests in COexposed patients but generally are not widely available in the ED [170][171][172]. SPECT in particular may correlate better than other neuroimaging findings with the development of delayed neurologic sequelae [173].…”

Section: Neuropsychometric Testingmentioning

confidence: 99%

Carbon monoxide poisoning

Kao¹,

Nañagas²

2004

Emergency Medicine Clinics of North America

167

171

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“…HMPAO SPECT cerebellar abnormalities [14] in children and CT cerebellar atrophy in adults have been described after treatment by HD ara-C [30]. In pathology, the most consistent finding is a loss of Purkinje cells in the cerebellar hemispheres and in the vermis.…”

Section: Discussionmentioning

confidence: 98%

“…HMPAO SPECT scan is a widely used method for cerebral perfusion studies and has been used to evaluate druginduced neurotoxicity [28][29][30]. Osterlundh et al [31] and Karabacak et al [32] reported cases of brain HMPAO SPECT abnormalities in children receiving methotrexate.…”

Section: Discussionmentioning

confidence: 99%

Brain Perfusion in Adult Patients with Acute Myeloblastic Leukemia before and after Cytosine Arabinoside

Modzelewski

Leprêtre²,

Martinaud

et al. 2010

Mol Imaging Biol

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Electroencephalographic mapping and 99mTc HMPAO single-photon emission computed tomography in carbon monoxide poisoning

Cited by 23 publications

References 18 publications

Serial Assessments of Delayed Encephalopathy after Carbon Monoxide Poisoning Using Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging on 3.0T System

Serial Assessments of Delayed Encephalopathy after Carbon Monoxide Poisoning Using Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging on 3.0T System

Carbon monoxide poisoning

Brain Perfusion in Adult Patients with Acute Myeloblastic Leukemia before and after Cytosine Arabinoside

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