Electrocoagulation of cancer of the rectum

Swerdlow, Dave B.; Salvati, Eugene P.

doi:10.1007/bf02589869

Cited by 9 publications

References 12 publications

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Contemporary management of rectal cancer.An overview

Jackson

1977

Cancer

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Surgery does not cure more than 50% of "curable" rectal cancers. Local, regional, and disseminated cancers unremoved and untreated by surgery and other modalities account for this unrelenting mortality for the past 20 years. The results and promise of current investigations in multimodality approaches are discussed. Studies on lymph node histopathology seem to offer reliable prognostic significance in local or regionally confined disease. The use of adjuvant preoperative radiation foretells increased curability rates by decreasing the pathologic staging and local recurrence rates. Trials are under way potentiating the effects of radiation on tumor cells by combining it with various methods of hyperthermia or radiosensitizing compounds. Recent reports on the use of anticoagulation therapy at the time of surgery to prevent tumor cell implantation in fibrin networks indicate that this therapy is reasonable and worthy of more trial. The use of localized treatment in carefully selected patients is reviewed, including excision with electrocoagulation and contact x-ray therapy popularized in France by Papillon. Our early results of treatment by an interstitial iridium 192 rectal template afterloading technique are impressive. While chemotherapy for rectal cancer has, in general, been of no benefit, the combination of methyl-CCNU, vincristine and 5-FU seems to offer a reasonable response rate. The most exciting modality at present is immunotherapy. We believe that the adequate destruction of local and regional disease by radiation and surgery, the prevention of recurrent local and regional disease by radiation and surgery, the prevention of its local extension and implantation of metastases by anticoagulation and chemotherapy, with the stimulation of the hosts' immune response or prevention of immunosuppression by immunotherapy, are the indicated multimodalities of contemporary treatment.

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Contemporary management of rectal cancer.An overview

Jackson

1977

Cancer

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Treatment alternatives: Localized rectal cancer

Stearns

Sternberg

DeCosse

1984

Cancer

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Cancers that occur in the low or mid rectum, and are superficial and freely movable on the underlying bowel wall, should be considered for local treatment provided they are not anaplastic and are technically accessible to excision. Although a variety of methods have been shown to be effective, we propose that initial local surgical excision as a "total biopsy" is the most rational approach to the management of such lesions. Factors indicating a poor prognosis, including extension through the entire thickness of the bowel wall, incomplete surgical excision, poorly differentiated histologic grading, venous or lymphatic invasion, or colloid type of tumor, can be identified, and more aggressive surgical treatment can be urged. When these factors are absent, the total biopsy then constitutes definitive treatment for this highly selected population.Cancer 54:2691-2694, 1984.OR THE MAJORITY of patients with large bowel F cancer, surgical resection, which is designed to encompass the tumor-bearing segment of the bowel and the lymphatics that drain the involved region, is appropriate, and subsequent function is excellent. For cancer

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Technical Problems of Carbon Dioxide Laser Surgery in the Rectum

Verschueren¹

1981

The Biomedical Laser

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Electrocoagulation of cancer of the rectum

Cited by 9 publications

References 12 publications

Contemporary management of rectal cancer.An overview

Contemporary management of rectal cancer.An overview

Treatment alternatives: Localized rectal cancer

Technical Problems of Carbon Dioxide Laser Surgery in the Rectum

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