1984
DOI: 10.1002/1097-0142(19841201)54:2+<2691::aid-cncr2820541414>3.0.co;2-2
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Treatment alternatives: Localized rectal cancer

Abstract: Cancers that occur in the low or mid rectum, and are superficial and freely movable on the underlying bowel wall, should be considered for local treatment provided they are not anaplastic and are technically accessible to excision. Although a variety of methods have been shown to be effective, we propose that initial local surgical excision as a "total biopsy" is the most rational approach to the management of such lesions. Factors indicating a poor prognosis, including extension through the entire thickness o… Show more

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Cited by 54 publications
(8 citation statements)
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“…On the presence of factors suggestive of bad prognosis, such as a deep lesion throughout the intestinal wall, incomplete surgical excision, presence of undifferentiated cells, venous or lymphatic invasion, and mucinous tumors, more aggressive and radical surgeries are indicated [36]. The final therapeutic decision must not be done before the complete examination of the tissue [9].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…On the presence of factors suggestive of bad prognosis, such as a deep lesion throughout the intestinal wall, incomplete surgical excision, presence of undifferentiated cells, venous or lymphatic invasion, and mucinous tumors, more aggressive and radical surgeries are indicated [36]. The final therapeutic decision must not be done before the complete examination of the tissue [9].…”
Section: Discussionmentioning
confidence: 99%
“…Despite that the literature on the local excision of rectal tumors indicates high survival rates and good results about the local control of the disease, selection criteria for patient are restrict. Only about 3 to 8% of invasive rectal tumors are qualified for this kind of treatment, based on those criteria [36,40]. From all available techniques for local excision of rectal lesions, the endoscopic procedures (TEM and others) are the most internationally used.…”
Section: Discussionmentioning
confidence: 99%
“…33 The final therapeutic decision must not be done before the complete examination of the tissue. 34 The advantage of having a tissue sample for the histopathological exam has been a stimulus for a complete local excision in selected patients.…”
Section: Discussionmentioning
confidence: 99%
“…Only about 3 to 8% of invasive rectal tumors are qualified for this kind of treatment, based on those criteria. 33,37 From all available techniques for local excision of rectal lesions, the endoscopic procedures (TEM and others) are the most internationally used. Nevertheless, these techniques demand experience and, in consequence, must be performed in reference centers where a larger number of patients are available, facing that the surgeon training is mandatory and the small frequency of the indications is a reality.…”
Section: Discussionmentioning
confidence: 99%
“…The indications for local excision of early rectal carcinomas have been advocated by several researchers in the last 20 years and the following criteria have been reached so far [1][2][3][4]. If locally excised specimens have well differentiated histology, no lymphatic or vessel invasion, and negative cut end, local excision is appropriate enough for the treatment of early invasive carcinomas.…”
Section: Introductionmentioning
confidence: 99%