Electrochemiluminescence of Acridines

Abstract

Acridines play an important role in various fields of sciences. Besides their application for treatment of a number of infections, cancer, viral and prion diseases, they have been extensively used in chemiluminescence. Electrochemiluminescence (ECL) is a unique kind of chemiluminescence with the precise temporal and spatial control of light emitting reactions by utilizing electrochemistry techniques. These advantages result in increasing attention towards acridines ECL. This review summarizes acridines used in ECL, ECL mechanisms, strategies for increasing ECL intensities, and ECL analytical applications, as well as prospects the future development of acridine ECL.

Monomer and Excimer Emission in Electrogenerated Chemiluminescence of Pyrene and 2,7-Di-tert-butylpyrene Associated with Electron Transfer Distance

“…Electrogenerated chemiluminescence (ECL) is a result of the radiative transition from excited states of a luminescent molecule (R*) produced by ion annihilation (electron transfer) between electrochemically generated radical anions (R •– ) and cations (R •+ ) from their parent molecule at the ground state (R), as − …”

“…Electrogenerated chemiluminescence (ECL) is a result of the radiative transition from excited states of a luminescent molecule (R*) produced by ion annihilation (electron transfer) between electrochemically generated radical anions (R •– ) and cations (R •+ ) from their parent molecule at the ground state (R), as − normalR + e − → R • − ( electrochemical reduction ) normalR − e − → R • + ( electrochemical oxidation ) R • − + R • + → R * + normalR ( ion annihilation ) …”

High-Efficiency CdSe Quantum Dots/Fe3O4@MoS2/S2O82– Electrochemiluminescence System Based on a Microfluidic Analysis Platform for the Sensitive Detection of Neuron-Specific Enolase

“…Electrochemiluminescence (ECL) is a special form of chemiluminescence. − In short, through the gain and loss of electrons, luminescent materials produce active intermediates, then reach the excited state, and finally convert the excited state back to the luminescent ground state. ,, Because of its high sensitivity and controllability, ECL has grown into an important electrochemical detection method. , Neuron-specific enolase (NSE) is one of the most sensitive markers of small cell lung cancer (SCLC). − It may indicate the occurrence of SCLC when the content of NSE exceeds the normal range level in the human body. Therefore, the development of an efficient NSE detection method combined with ECL technology has an important application value for the diagnosis and treatment of SCLC.…”