Electrochemically induced chain transformation of salicylaldehydes and alkyl cyanoacetates into substituted 4H-chromenes

Catalysis of Cascade and Multicomponent Reactions of Carbonyl Compounds and CH Acids by Electricity

“…An electrochemically induced reaction of salicylaldehydes and two molecules of cyanoacetate resulted in 2‐amino‐4 H ‐chromenes 7 formation, with 900–1000% current efficiency (Scheme ) 38…”

Synthesis, Characterization and In Vitro Antibacterial Effect of 4H-Benzo[g]chromene Derivatives using Nano-NiO

“…It is one of the privileged scaffolds with a medicinal pharmacophore such as antivascular, antimicrobial, antioxidant, anticoagulant, estrogenic, anti-helminthic, anticancer 1 , anti-HIV, anti-inflammatory 2 , analgesic, herbicidal 3 and anticonvulsant. Chromenes are an important natural occurring compound such as flavonoids, alkaloids, tocopherol and anthocyanin [4][5][6] . Benzo[g]chromene contains naphthoquinone structural motifs which also have a broad spectrum in biological activities, as molecular probes for biochemical research 7 , emitters in electroluminescence devices and as fluorescent whitening agents 8 .…”

Greener One-pot Synthesis of Chromeno Oxazin and Oxazin Quinoline Derivatives and their Antibacterial Activity

“…The main importance lies in the functionally substituted chromenes in the field of medicinal chemistry [22][23] as natural fruit and plant extract in Ammi Visnaga as visnadine [25] and in Phlojodicarpus sibiricus as Khellactone [26]. These have perfect vasodilatory properties.…”