Electrochemical Sensitive Determination of Nanomolar Guanine from ZnO Nanorods Coated on Platinum Electrode

Abstract

The crystalline ZnO nanorods, grown on Si‐substrate (100) at a low temperature using a hydrothermal process were used for modification of platinum electrode using PVC and THF for in order to test their chemosensor activity. The modified electrode can be used for selective nanomolar determination of guanine in aqueous media without any interference from other biomolecules. The prepared chemosensor has a lower detection limit of 40 nM for guanine, and a modification of the electrodes with ZnO nanorods increases the reproducibility by reducing the fouling effect caused by the oxidation of biomolecules on the electrode surface as the prepared electrode can be used for more than 30 consecutive scans and can be used for 5 days without any change in current intensity or sensitivity.

A Survey on Current-Mode Interfaces for Bio Signals and Sensors

“…A subset of electrochemical sensors is represented by molecular sensors, which can perform molecular recognition in solutions, blood, air, etc. [ 77 ]. At the same time, optical biosensors are finding increasing applications because they provide a non-invasive way to measure the same quantities [ 76 , 78 , 79 , 80 , 81 ] and ease in converting optical signals into electrical form.…”